MRI-based study of 3He gas diffusion in lungs may provide important information on lung
microstructure. Lung acinar airways can be described in terms of cylinders covered with …

The need for airway imaging is defined by the limited sensitivity of common clinical tests like
spirometry, lung diffusion (DLCO) and blood gas analysis to early changes of peripheral …

Abstracts Unlike any other organ, imaging of lungs with magnetic resonance faces unique
challenges owing to the complex microstructure and presence of gas-tissue interfaces. With …

Traditional magnetic resonance imaging (MRI) uses the NMR signal from protons to obtain
images in the human body. The technique enables detailed imaging of brain and soft tissue …

Several studies have reported apparent diffusion coefficient (ADC) values of 3He gas in the
lung, however few have explored the dependence of these ADC values on the effective …

The noninvasive assessment of lung function using imaging is increasingly of interest for the
study of lung diseases, including chronic obstructive pulmonary disease (COPD) and …

Lung diseases affect the conducting airways, the gas exchange parenchyma, or both. As a
result, they have a high impact on patients' morbidity, and quality of life. Chronic obstructive …

AbstractThe current status of experimental and clinical applications for functional MR
imaging of pulmonary ventilation using hyperpolarized noble gases are reviewed. 3-helium …

The 3He lung morphometry technique (Yablonskiy et al., JAP, 2009), based on MRI
measurements of hyperpolarized gas diffusion in lung airspaces, provides unique …

Despite a long history of development, diagnostic tools for in vivo regional assessment of
lungs in patients with pulmonary emphysema are not yet readily available. Recently, a new …