An optimized interleaved‐spiral pulse sequence, providing high spatial and temporal
resolution, was developed for dynamic imaging of pulmonary ventilation with hyperpolarized …

The invention of hyperpolarized (HP) noble gas MRI using helium-3 (3 He) or xenon-129
(129 Xe) has provided a new method to evaluate lung function. Using HP 3 He or 129 Xe for …

Lung ventilation was mapped in five healthy Brown Norway rats (210–377 g) using both
hyperpolarized 3He MRI and Xe‐enhanced computed tomography (Xe‐CT) under similar …

MR studies of the human lung with hyperpolarized 3 He have demonstrated the potential to
acquire high-resolution, but static, images of lung ventilation [1-3]. Given the high signal …

Purpose To evaluate regional anisotropy of lung‐airspace orientation by assessing the
dependence of helium‐3 (3He) apparent diffusion coefficient (ADC) values on the direction …

Pulmonary functional magnetic resonance imaging (PfMRI) provides a way to non-invasively
map and measure the spatial distribution of pulmonary ventilation, perfusion and gas …

Effective pulmonary gas exchange relies on the free diffusion of gases across the thin tissue
barrier separating airspace from the capillary red blood cells (RBCs). Pulmonary …

During the measurement of hyperpolarized 129Xe magnetic resonance imaging (MRI), the
diffusion‐weighted imaging (DWI) technique provides valuable information for the …

Hyperpolarized 129 Xe magnetic resonance imaging is a powerful modality capable of
assessing lung structure and function. While it has shown promise as a clinical tool for the …

RATIONALE AND OBJECTIVES: The use of hyperpolarized 3He magnetic resonance
imaging as a quantitative lung imaging tool has progressed rapidly in the past decade …