Throughout life, individuals experience a vast array of positive and aversive events that
trigger adaptive behavioural responses. These events are often unpredicted and engage …

Throughout life, individuals experience a vast array of positive and aversive events that
trigger adaptive behavioural responses. These events are often unpredicted and engage …

There has been a growing interest in understanding the role of the lateral habenula (LHb) in
reward processing, affect regulation, and goal-directed behaviors. The LHb gets major …

The brain's ability to associate threats with external stimuli is vital to execute essential
behaviours including avoidance. Disruption of this process contributes instead to the …

The lateral habenula (LHb) is a phylogenetically primitive brain structure that plays a key
role in learning to inhibit distinct responses to specific stimuli. This structure is activated by …

The evolutionarily conserved lateral habenula (LHb) enables dynamic responses to
continually changing contexts and environmental conditions. A model is proposed to …

Animals constantly adjust their actions based on new experiences. Thus, rewarding
experiences and non-rewarding or aversive experiences are integrated to guide behaviors …

In this Perspective review, we highlight some of the less explored aspects of lateral
habenula (LHb) function in contextual memory, sleep, and behavioral flexibility. We provide …

The lateral habenula (LHb) regulates reward learning and controls the updating of reward-
related information. Drugs of abuse have the capacity to hijack the cellular and neurocircuit …

The lateral habenula (LHb) is believed to encode negative motivational values. It remains
unknown how LHb neurons respond to various stressors and how learning shapes their …