Managing hypertension in high-risk patients: lessons and promises from the STRATHE and ADVANCE trials

B Waeber - Journal of Hypertension, 2006 - journals.lww.com
Pharmacological treatment of hypertension represents a cost-effective way of preventing
cardiovascular and renal complications. To benefit maximally from antihypertensive …

The need for combination antihypertensive therapy to reach target blood pressures: what has been learned from clinical practice and morbidity–mortality trials?

HAJ Struijker‐Boudier, E Ambrosioni… - … journal of clinical …, 2007 - Wiley Online Library
Pharmacological treatment of hypertension represents a cost‐effective way for preventing
cardiovascular and renal complications. To benefit maximally from antihypertensive …

Management of high blood pressure in type 2 diabetes: perindopril/indapamide fixed-dose combination and the ADVANCE trial

L Ghiadoni - Expert Opinion on Pharmacotherapy, 2010 - Taylor & Francis
Importance of the field: The increase in type 2 diabetes mellitus is associated to
cardiovascular morbidity and mortality. This review focuses on the benefits of the fixed-dose …

Hypertension 2010: what was new for the cardiologist?

Z Gaciong, B Symonides - Expert Opinion on Pharmacotherapy, 2010 - Taylor & Francis
Importance of the field: Despite extensive clinical research, still there is some uncertainty
regarding management of hypertension, in particular initial and goal blood pressure levels …

Rationale and design of the ADVANCE study: a randomised trial of blood pressure lowering and intensive glucose control in high-risk individuals with type 2 diabetes …

J Chalmers - Journal of Hypertension, Supplement, 2001 - researchnow.flinders.edu.au
Rationale Individuals with type 2 diabetes mellitus have an increased risk of vascular
disease, which is reduced by lowering the blood pressure of patients with hypertension …

Are current strategies for treating hypertension effective?

DA Sica - Journal of Clinical Hypertension (Greenwich, Conn.), 2003 - europepmc.org
The ultimate goal of hypertension management is to prevent or reverse target organ damage
and thereby to reduce cardiovascular and renal morbidity and mortality. Over the past two …

Implications of the ADVANCE study for clinical practice

F Zannad - Journal of Hypertension, 2008 - journals.lww.com
Blood pressure is an important determinant of the risk of macro-and microvascular vascular
complications in patients with type 2 diabetes. Current European guidelines for the …

Managing hypertension: a question of STRATHE

F Zannad - Journal of human hypertension, 2005 - nature.com
Current international guidelines recommend the use of therapeutic strategies with proven
efficacy in the management of hypertension to achieve a target blood pressure of< 140/90 …

Is it time to move to multidrug combinations?

JL Pool - American journal of hypertension, 2003 - academic.oup.com
The clinical benefit of aggressive blood pressure (BP) control in reducing adverse
cardiovascular and renal outcomes is well documented. However, a majority of patients with …

Hypertension: which aspects of hypertension should we impact on and how?

A Zanchetti, B Waeber - Journal of Hypertension, 2006 - journals.lww.com
Cardiovascular complications may, to a large extent, be prevented by lowering blood
pressure in hypertensive patients. International recommendations currently stress the …