Approaches for the synthesis, chemical modification and biological properties of N-acylphenothiazines
In this review we systematized the theoretical and experimental data concerning the
versatile approaches for the synthesis of N-acylphenothiazines. The aim of the study was to …
versatile approaches for the synthesis of N-acylphenothiazines. The aim of the study was to …
Recent progress in synthesis, structure and biological activities of phenothiazine derivatives
C Gopi, MD Dhanaraju - Review Journal of Chemistry, 2019 - Springer
The phenothiazine nucleus is one of the most important and trusted heterocyclic ring, which
is commonly found in natural products and medicinal agents. It was discovered during the …
is commonly found in natural products and medicinal agents. It was discovered during the …
Recent advances in the medicinal chemistry of phenothiazines, new anticancer and antiprotozoal agents
A González-González… - Current Medicinal …, 2021 - ingentaconnect.com
Background: Molecules with a phenothiazine scaffold have been considered versatile
organic structures with a wide variety of biological activities, such as antipsychotic …
organic structures with a wide variety of biological activities, such as antipsychotic …
Computational Studies and Synthesis of New Heterocyclics as CNS Agents
Aim: This research work aimed to design and synthesize some new molecules of
phenothiazine. The work's emphasis was on forming new phenothiazines in two series, 1 …
phenothiazine. The work's emphasis was on forming new phenothiazines in two series, 1 …
Retrosynthetic approach to the synthesis of phenothiazines
IA Silberg, G Cormos, DC Oniciu - Advances in heterocyclic chemistry, 2006 - Elsevier
The first compound containing a phenothiazine ring, 3, 7-diaminophenazathionium chloride,
was obtained in 1876 by Lauth (1876CB1035). Bernthsen synthesized the parent …
was obtained in 1876 by Lauth (1876CB1035). Bernthsen synthesized the parent …
Recent progress in biological activities of synthesized phenothiazines
K Pluta, B Morak-Młodawska, M Jeleń - European journal of medicinal …, 2011 - Elsevier
This review summarizes recent medicinal chemistry investigations in vitro and in vivo in
search for new phenothiazines of promising biological activities. New phenothiazine …
search for new phenothiazines of promising biological activities. New phenothiazine …
A multifaceted scaffold for building bioactive compounds: Phenothiazine
In the growing field of heterocyclic compounds, phenothiazine and the associated nucleus
are among the most significant potential scaffolds with excellent pharmacological activities …
are among the most significant potential scaffolds with excellent pharmacological activities …
Antitumor Potential and Possible Targets of Phenothiazine Derivatives: A Recent Review
The unique chemical characteristics of the phenothiazine ring system have been a major
driving force for the development of various phenothiazine-based compounds with a huge …
driving force for the development of various phenothiazine-based compounds with a huge …
Synthetic methods of medicinally important heterocycles-thiazines: A review
Heterocyclic compounds containing N and S atoms have unique properties so that they can
be used as potential reactive materials in pharmacokinetic systems. In medicinal chemistry …
be used as potential reactive materials in pharmacokinetic systems. In medicinal chemistry …
[PDF][PDF] Synthesis and Evaluation of Phenothiazine Derivatives
Background: Phenothiazine is one of the protypical pharmaceutical lead molecules in
medicinal chemistry. Derivatives of phenothiazines are highly bioactive and have …
medicinal chemistry. Derivatives of phenothiazines are highly bioactive and have …