[HTML][HTML] Multiple functions of the DEAD-box RNA helicase, DDX5 (p68), make DDX5 a superior oncogenic biomarker and target for targeted cancer therapy
Abstract DDX5 (p68) is a well-known multifunctional DEAD-box RNA helicase and a
transcription cofactor. Since its initial discovery more than three decades ago, DDX5 is …
transcription cofactor. Since its initial discovery more than three decades ago, DDX5 is …
A double-edged function of DDX3, as an oncogene or tumor suppressor, in cancer progression
Y He, D Zhang, Y Yang, X Wang… - Oncology …, 2018 - spandidos-publications.com
Abstract DEAD-box RNA helicase 3 (DDX3) is a highly conserved family member of DEAD-
box proteins in all eukaryotes from yeasts to human beings. Accumulating studies have …
box proteins in all eukaryotes from yeasts to human beings. Accumulating studies have …
Roles of DDX5 in the tumorigenesis, proliferation, differentiation, metastasis and pathway regulation of human malignancies
RM Nyamao, J Wu, L Yu, X Xiao, FM Zhang - Biochimica et Biophysica Acta …, 2019 - Elsevier
The DEAD-box RNA helicase DDX5 is a member of a family of highly conserved proteins
involved in gene-expression regulation and ATP-dependent RNA helicase activities …
involved in gene-expression regulation and ATP-dependent RNA helicase activities …
DDX5 and DDX17—multifaceted proteins in the regulation of tumorigenesis and tumor progression
K Xu, S Sun, M Yan, J Cui, Y Yang, W Li… - Frontiers in …, 2022 - frontiersin.org
DEAD-box (DDX) 5 and DDX17, which belong to the DEAD-box RNA helicase family, are
nuclear and cytoplasmic shuttle proteins. These proteins are expressed in most tissues and …
nuclear and cytoplasmic shuttle proteins. These proteins are expressed in most tissues and …
DDX3X multifunctionally modulates tumor progression and serves as a prognostic indicator to predict cancer outcomes
TC Lin - International journal of molecular sciences, 2019 - mdpi.com
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-Linked (DDX3X), also known as DDX3, is
one of the most widely studied and evolutionarily conserved members of the DEAD-box …
one of the most widely studied and evolutionarily conserved members of the DEAD-box …
Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human …
F Li, X Ling, S Chakraborty, C Fountzilas… - Journal of Experimental …, 2023 - Springer
There is increasing evidence indicating the significant role of DDX5 (also called p68), acting
as a master regulator and a potential biomarker and target, in tumorigenesis, proliferation …
as a master regulator and a potential biomarker and target, in tumorigenesis, proliferation …
DEAD-box RNA helicases DDX3X and DDX5 as oncogenes or oncosuppressors: A network perspective
M Secchi, C Lodola, A Garbelli, S Bione, G Maga - Cancers, 2022 - mdpi.com
Simple Summary The transformation of a normal cell into a cancerous one is caused by the
deregulation of different metabolic pathways, involving a complex network of protein–protein …
deregulation of different metabolic pathways, involving a complex network of protein–protein …
Pan-cancer analysis of the prognostic and immunological roles of DEAD-box helicase 5 (DDX5) in human tumors
S Liu, Y Liu, X Zhang, X Song, B Zhang… - Frontiers in …, 2022 - frontiersin.org
Background: Recent studies have demonstrated the significance of the DEAD-box helicase
5 (DDX5) gene, which is involved in pathways concerning the modification of RNA …
5 (DDX5) gene, which is involved in pathways concerning the modification of RNA …
DDX3X: structure, physiologic functions and cancer
J Mo, H Liang, C Su, P Li, J Chen, B Zhang - Molecular cancer, 2021 - Springer
The DEAD-box helicase family member DDX3X (DBX, DDX3) functions in nearly all stages
of RNA metabolism and participates in the progression of many diseases, including virus …
of RNA metabolism and participates in the progression of many diseases, including virus …
[HTML][HTML] DDX21 interacts with WDR5 to promote colorectal cancer cell proliferation by activating CDK1 expression
P Lu, Z Yu, K Wang, Y Zhai, B Chen, M Liu, P Xu… - Journal of …, 2022 - ncbi.nlm.nih.gov
Abstract DEAD-box RNA helicase 21 (DDX21), is a nucleolar protein harboring ATP-
dependent double-stranded RNA unwinding activities, essential in rRNA processing and …
dependent double-stranded RNA unwinding activities, essential in rRNA processing and …