Genetics of cardiovascular disease: fishing for causality

C Paone, F Diofano, DD Park, W Rottbauer… - Frontiers in …, 2018 - frontiersin.org
Cardiovascular disease (CVD) is still the leading cause of death in all western world
countries and genetic predisposition in combination with traditional risk factors frequently …

Genetics and genomics for the prevention and treatment of cardiovascular disease: update: a scientific statement from the American Heart Association

SK Ganesh, DK Arnett, TL Assimes, CT Basson… - Circulation, 2013 - Am Heart Assoc
This update expands the prior scientific statement on the relevance of genetics and
genomics for the prevention and treatment of CVDs. 2 In the earlier report, we focused on …

[图书][B] Human genetics and big data to guide cardiovascular drug development

AJ Cupido - 2023 - pure.uva.nl
It has been over 150 years since Gregor Mendel conducted his first experiments using peas,
thereby establishing the foundation of modern genetics. Since then, further advances in …

Exploring predisposition and treatment response—the promise of genomics

S Pan, JW Knowles - Progress in cardiovascular diseases, 2012 - Elsevier
Spurred by large-scale public and private efforts as well as technological developments, the
last few years have seen a major leap forward in our understanding of the genetic basis of …

Large-scale genome-wide association studies consortia: blessing, burden, or necessity?

E Ingelsson - Circulation: Cardiovascular Genetics, 2010 - Am Heart Assoc
ARtery DIsease Genome-wide Replication And Meta-Analysis (CARDIoGRAM) consortium.
CARDIoGRAM is one of several consortia that have formed in the past few years in order to …

[PDF][PDF] Genetics and Genomics for the Prevention and Treatment of Cardiovascular Disease: Update

TL Assimes, CT Basson, A Chakravarti, PT Ellinor… - Circulation, 2013 - scholar.archive.org
This update expands the prior scientific statement on the relevance of genetics and
genomics for the prevention and treatment of CVDs. 2 In the earlier report, we focused on …

[PDF][PDF] Unveiling shared genetic pathways in cardiovascular diseases: towards personalized therapies and holistic treatment approaches

JS Tan, ZQ Liu, YM Wang, S Hu, YR Deng, LT Chong… - tmrjournals.com
Cardiovascular diseases (CVDs), encompassing diverse pathologies such as
atherosclerosis, hypertension, cardiomyopathy, arrhythmia, and valvular diseases, represent …

Life after GWAS: functional genomics in vascular biology

AJ Lusis - Arteriosclerosis, thrombosis, and vascular biology, 2012 - Am Heart Assoc
The genome-wide association studies (GWAS) of recent years have provided the first
unbiased views of genes contributing to cardiovascular disorders in European and some …

Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association

CS Fox, JL Hall, DK Arnett, EA Ashley, C Delles… - Circulation, 2015 - Am Heart Assoc
The field of genetics and genomics has advanced considerably with the achievement of
recent milestones encompassing the identification of many loci for cardiovascular disease …

Genomic insights into heart health: Exploring the genetic basis of cardiovascular disease

M Safdar, M Ullah, A Wahab, S Hamayun… - Current Problems in …, 2024 - Elsevier
Cardiovascular diseases (CVDs) are considered as the leading cause of death worldwide.
CVD continues to be a major cause of death and morbidity despite significant improvements …