Cystic fibrosis (CF) is an autosomal recessive disease that is caused by mutations in the
cystic fibrosis conductance regulator (CFTR) gene and usually presents with multiorgan …

In the healthy lung the opportunistic pathogen, Pseudomonas aeruginosa, is rapidly
eliminated by mucociliary clearance, a process that is dependent on the activity of the CFTR …

The current pathophysiological model of cystic fibrosis lung disease assumes that defective
expression, trafficking, or function of the cystic fibrosis transmembrane regulator (CFTR) …

Cystic Fibrosis (CF) is the most commonly inherited, life-shortening genetic condition
amongst Caucasians, with an incidence of about 1 in 3,800 newborns and currently affecting …

Cystic fibrosis (CF) is a lethal genetic disease that affects 30,000 people in the United States
alone. While the disease affects organs throughout the body, it is the lung disease that is the …

The pathogenesis of cystic fibrosis (CF) airways infection is unknown. Two hypotheses,"
hypotonic [low salt]/defensin" and" isotonic volume transport/mucus clearance," attempt to …

Cystic Fibrosis on emaze Cystic Fibrosis Alexis Mejia and Philly G. Cell to cell communication
-Cells communicate by sending and receiving signals -Signals may come from the …

Background The purpose of this study was to compare vectorial ion transport within murine
trachea, murine nasal septa, and human sinonasal cultured epithelium. Our hypothesis is …

The airways are lined with a film of liquid about 10 µm deep that is in two layers. Around the
cilia is the watery periciliary sol. Over this is a mucous blanket that traps inhaled particles …