Background: Osteoporosis is a common degenerative bone disease which is characterized
with decreased bone strength and increased risk of fracture. The abnormal bone metabolism …

Osteoporosis is a metabolic disease characterized by decreased bone mineral density and
the destruction of bone microstructure, which can lead to increased bone fragility and risk of …

Epigenetic modification pertains to the alteration of genetic-expression, which could be
transferred to the next generations, without any alteration in the fundamental DNA …

Osteoporosis is a complex multifactorial condition of the musculoskeletal system.
Osteoporosis and osteoporotic vertebral fracture (OVF) are associated with high medical …

Bone regeneration is a promising avenue for osteoporosis (OP) treatment. It consists of
several procedures, such as the osteogenic differentiation of mesenchymal stem cells as …

Epigenetics describes mechanisms which control gene expression and cellular processes
without changing the DNA sequence. The main mechanisms in epigenetics are DNA …

Bone is a major organ in the skeletal system that supports and protects muscles and other
organs, facilitates movement and hematopoiesis, and forms a reservoir of minerals including …

In bone biology, epigenetics plays a key role in mesenchymal stem cells'(MSCs)
commitment towards osteoblasts. It involves gene regulatory mechanisms governed by …

Bone turnover is sophisticatedly balanced by a dynamic coupling of bone formation and
resorption at various rates. The orchestration of this continuous remodeling of the skeleton …

Osteoporosis is a common form of metabolic bone disease that is costly to treat and is
primarily diagnosed on the basis of bone mineral density. As the influences of genetic …