Anticancer molecular mechanisms of oleocanthal
M El Haouari, JE Quintero… - Phytotherapy Research, 2020 - Wiley Online Library
Cancer is among the leading causes of mortality worldwide. Current cancer therapies are
associated with serious side effects, which further damage patients' health. Therefore, the …
associated with serious side effects, which further damage patients' health. Therefore, the …
[HTML][HTML] (−)-Oleocanthal induces death preferentially in tumor hematopoietic cells through caspase dependent and independent mechanisms
C Pastorio, S Torres-Rusillo, J Ortega-Vidal… - Food & Function, 2022 - pubs.rsc.org
Olive oil is a key component of the highly cardiovascular protective Mediterranean diet.(−)-
Oleocanthal (OLC) is one of the most interesting phenolics present in virgin olive oil, and is …
Oleocanthal (OLC) is one of the most interesting phenolics present in virgin olive oil, and is …
Anticancer effects of oleuropein
H Shamshoum, F Vlavcheski, E Tsiani - Biofactors, 2017 - Wiley Online Library
Cancer cells exhibit enhanced proliferation rate and a resistance to apoptosis.
Epidemiological studies suggest that olive oil intake is associated with a reduced risk of …
Epidemiological studies suggest that olive oil intake is associated with a reduced risk of …
[HTML][HTML] Current disease-targets for oleocanthal as promising natural therapeutic agent
A Segura-Carretero, JA Curiel - International Journal of Molecular …, 2018 - mdpi.com
The broad number of health benefits which can be obtained from the long-term consumption
of olive oil are attributed mainly to its phenolic fraction. Many olive oil phenolics have been …
of olive oil are attributed mainly to its phenolic fraction. Many olive oil phenolics have been …
[HTML][HTML] Oleanolic acid alters multiple cell signaling pathways: implication in cancer prevention and therapy
Nowadays, much attention has been paid to diet and dietary supplements as a cost-effective
therapeutic strategy for prevention and treatment of a myriad of chronic and degenerative …
therapeutic strategy for prevention and treatment of a myriad of chronic and degenerative …
Cytotoxic activity of oleocanthal isolated from virgin olive oil on human melanoma cells
Oleocanthal is one of the phenolic compounds of extra virgin olive oil with important anti-
inflammatory properties. Although its potential anticancer activity has been reported, only …
inflammatory properties. Although its potential anticancer activity has been reported, only …
[HTML][HTML] (-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells
L Goren, G Zhang, S Kaushik, PAS Breslin, YCN Du… - PLoS …, 2019 - journals.plos.org
(-)-Oleocanthal (oleocanthal) is a phenolic compound found in varying concentrations in
extra virgin olive oil oleocanthal has been shown to be active physiologically, benefiting …
extra virgin olive oil oleocanthal has been shown to be active physiologically, benefiting …
[HTML][HTML] Anticancer activity of oleanolic acid and its derivatives: Recent advances in evidence, target profiling and mechanisms of action
ZY Tang, Y Li, YT Tang, XD Ma, ZY Tang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract Oleanolic acid (OA, 3 β-hydroxyoleanolic acid-12-en-28-oic acid) is a pentacyclic
triterpenoid present in many plants. As a new framework for development of semi synthetic …
triterpenoid present in many plants. As a new framework for development of semi synthetic …
[HTML][HTML] Oleuropein and cancer chemoprevention: the link is hot
A Ahmad Farooqi, S Fayyaz, AS Silva, A Sureda… - Molecules, 2017 - mdpi.com
Cancer comprises a collection of related diseases characterized by the existence of altered
cellular pathways resulting in an abnormal tendency for uncontrolled growth. A broad …
cellular pathways resulting in an abnormal tendency for uncontrolled growth. A broad …
[HTML][HTML] Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generation
A Cusimano, D Balasus… - International …, 2017 - spandidos-publications.com
The beneficial health properties of the Mediterranean diet are well recognized. The principle
source of fat in Mediterranean diet is extra-virgin olive oil (EVOO). Oleocanthal (OC) is a …
source of fat in Mediterranean diet is extra-virgin olive oil (EVOO). Oleocanthal (OC) is a …