Increased prevalence of mutant allele Pfdhps 437G and Pfdhfr triple mutation in Plasmodium falciparum isolates from a rural area of Gabon, three years after the …

JMN Ngomo, DP Mawili-Mboumba… - Malaria Research …, 2016 - Wiley Online Library
In Gabon, sulfadoxine-pyrimethamine (SP) is recommended for intermittent preventive
treatment during pregnancy (IPTp-SP) and for uncomplicated malaria treatment through …

[HTML][HTML] High prevalence of mutation in the Plasmodium falciparum dhfr and dhps genes in field isolates from Sabah, Northern Borneo

NR Abdullah, NA Norahmad, J Jelip, LH Sulaiman… - Malaria journal, 2013 - Springer
Background Sulphadoxine-pyrimethamine (SP) has been in use for the treatment of
uncomplicated falciparum malaria in Malaysia since the 1970s and is still widely employed …

[HTML][HTML] Molecular identification of sulfadoxine-pyrimethamine resistance in malaria infected women who received intermittent preventive treatment in the Democratic …

E Ruh, JP Bateko, T Imir, A Taylan-Ozkan - Malaria Journal, 2018 - Springer
Abstract Background Point mutations in Plasmodium falciparum dihydrofolate reductase
(Pfdhfr) and dihydropteroate synthase (Pfdhps) genes which confer resistance to …

[HTML][HTML] Evaluation of prevalence's of pfdhfr and pfdhps mutations in Angola

F Fortes, R Dimbu, P Figueiredo, Z Neto… - Malaria Journal, 2011 - Springer
Background Malaria is the major cause of morbidity and mortality in Angola. The most
vulnerable groups to Plasmodium falciparum infection are pregnant women and children …

[HTML][HTML] Increased prevalence of pfdhfr and pfdhps mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from Jazan …

AM Madkhali, HM Al-Mekhlafi, WM Atroosh… - Malaria journal, 2020 - Springer
Background Despite significant progress in eliminating malaria from the Kingdom of Saudi
Arabia, the disease is still endemic in the southwestern region of the country. Artesunate …

Prevalence of Plasmodium falciparum resistance markers to sulfadoxine-pyrimethamine among pregnant women receiving intermittent preventive treatment for …

AK Mbonye, J Birungi, SK Yanow… - Antimicrobial Agents …, 2015 - Am Soc Microbiol
The aim of this study was to assess the prevalence of mutations in Plasmodium falciparum
dihydrofolate reductase (Pfdhfr) and dihydropteroate synthase (Pfdhps) genes among …

Prevalence of Plasmodium falciparum parasites resistant to sulfadoxine/pyrimethamine in pregnant women in Yaoundé, Cameroon: emergence of highly resistant …

P Chauvin, S Menard, X Iriart… - Journal of …, 2015 - academic.oup.com
Objectives To determine, 6 years after the adoption of intermittent preventive treatment of
pregnant women with sulfadoxine/pyrimethamine (IPTp-SP) in Cameroon,(i) the …

[HTML][HTML] Occurrence of septuple and elevated Pfdhfr-Pfdhps quintuple mutations in a general population threatens the use of sulfadoxine-pyrimethamine for malaria …

GM Bwire, WP Mikomangwa, M Kilonzi - BMC Infectious Diseases, 2020 - Springer
Background Plasmodium falciparum dihydrofolate reductase (Pfdhfr) and dihydropteroate
synthetase (Pfdhps) mutations compromise the effectiveness of sulfadoxine-pyrimethamine …

[HTML][HTML] Molecular characterization of Plasmodium falciparum antifolate resistance markers in Thailand between 2008 and 2016

R Sugaram, K Suwannasin, C Kunasol, VB Mathema… - Malaria journal, 2020 - Springer
Background Resistance to anti-malarials is a major threat to the control and elimination of
malaria. Sulfadoxine–pyrimethamine (SP) anti-malarial treatment was used as a national …

[HTML][HTML] High prevalence of PfdhfrPfdhps quadruple mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from …

T Jiang, J Chen, H Fu, K Wu, Y Yao, JUM Eyi… - Malaria journal, 2019 - Springer
Background Sulfadoxine–pyrimethamine (SP) is recommended for intermittent preventive
treatment of malaria in Africa. However, increasing SP resistance (SPR) affects the …