Despite more than a century of research, the causative agent (s) in sarcoidosis, a
heterogeneous granulomatous disorder mainly affecting the lungs, remain (s) elusive …

Evidence points at microenvironment and cell functional features rather than cell
polarization or differentiation as determinants of pathogenesis. In terms of therapeutic …

Sarcoidosis is a multisystem granulomatous disorder invariably affecting the lungs. It is a
disease with noteworthy variations in clinical manifestation and disease outcome and has …

Introduction: Sarcoidosis is a multi-systemic granulomatous disease of unknown aetiology.
Ethnicity and environmental factors may influence disease incidence, phenotype and …

Thoracic sarcoidosis is the most common form of sarcoidosis, encompassing a
heterogeneous group of patients with a wide range of clinical features and associated …

Sarcoidosis is a systemic disease of unknown etiology characterized by the presence of
noncaseating granulomas that can occur in any organ, most commonly the lungs. Early and …

Sarcoidosis is a systemic inflammatory disorder characterised by tissue infiltration by
mononuclear phagocytes and lymphocytes with associated non-caseating granuloma …

Every year the knowledge on mediators, receptors, and, during the last years, on genes
possibly involved in sarcoidosis is growing. Nevertheless, its cause, its large variability, and …

Introduction: The pathogenesis of sarcoidosis is not yet completely understood, although in
recent years our knowledge has made considerable progress. Areas covered: This review …

Sarcoidosis continues to be a disease of research interest because of its complicated
immune mechanisms and elusive etiology. So far, it has been established that …