The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Host-guest motifs are likely the most recognizable manifestation of supramolecular
chemistry. These complexes are characterized by the organization of small molecules on the …

Supramolecular chemistry has its roots in biology and medicine. The fundamental principles
of host–guest chemistry can be traced to the ''lock and key''interactions between enzymes …

Classic prodrug strategies rely on covalent modification of active drugs to provide systems
with superior pharmacokinetic properties than the parent drug and facilitate administration …

Designing therapeutics is a process with many challenges. Even if the first hurdle—
designing a drug that modulates the action of a particular biological target in vitro—is …

Supramolecular chemistry provides a means to integrate multi-type molecules leading to a
dynamic organization. The study of functional nanoscale drug-delivery systems based on …

Poor water solubility and low bioavailability of active pharmaceutical ingredients (APIs) are
major causes of friction in the pharmaceutical industry and represent a formidable hurdle for …

This review focuses on the smart chemistry that has been utilized in developing polymer-
based drug delivery systems over the past 10 years. We provide a comprehensive overview …

Conspectus Delivery remains a major obstacle restricting the potential action of small
molecular drugs as well as novel biologics which cannot readily enter cells without the help …

Recent advances in supramolecular chemistry have had significant influence on the
biomedical applications of materials chemistry. Supramolecular systems are based on weak …