SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters

PJ Halfmann, S Iida, K Iwatsuki-Horimoto, T Maemura… - Nature, 2022 - nature.com
The recent emergence of B. 1.1. 529, the Omicron variant,, has raised concerns of escape
from protection by vaccines and therapeutic antibodies. A key test for potential …

Effects of COVID-19 vaccination and previous infection on Omicron SARS-CoV-2 infection and relation with serology

B de Gier, AJ Huiberts, CE Hoeve, G den Hartog… - Nature …, 2023 - nature.com
An increasing proportion of the population has acquired immunity through COVID-19
vaccination and previous SARS-CoV-2 infection, ie, hybrid immunity, possibly affecting the …

[HTML][HTML] Antibody evasion properties of SARS-CoV-2 Omicron sublineages

S Iketani, L Liu, Y Guo, L Liu, JFW Chan, Y Huang… - Nature, 2022 - nature.com
The identification of the Omicron (B. 1.1. 529.1 or BA. 1) variant of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) in Botswana in November 2021 1 immediately …

Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera

A Muik, BG Lui, AK Wallisch, M Bacher, J Mühl… - Science, 2022 - science.org
The globally circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant of concern Omicron (B. 1.1. 529) has a large number of mutations, especially in the …

[HTML][HTML] Antibody titers and breakthrough infections with Omicron SARS-CoV-2

C Dimeglio, M Migueres, JM Mansuy… - The Journal of …, 2022 - ncbi.nlm.nih.gov
Recent studies indicated that the strong immune evasion potential of the most recent SARS-
CoV-2 variant, Omicron, results in more frequent reinfections and breakthrough infections …

Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

B Meng, A Abdullahi, IATM Ferreira, N Goonawardane… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in 2021 and has multiple
mutations in its spike protein. Here we show that the spike protein of Omicron has a higher …

Attenuated replication and pathogenicity of SARS-CoV-2 B. 1.1. 529 Omicron

H Shuai, JFW Chan, B Hu, Y Chai, TTT Yuen, F Yin… - Nature, 2022 - nature.com
Abstract The Omicron (B. 1.1. 529) variant of SARS-CoV-2 emerged in November 2021 and
is rapidly spreading among the human population. Although recent reports reveal that the …

Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys

C Fenwick, P Turelli, D Ni, L Perez, K Lau… - Nature …, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant has very high levels of transmission, is resistant
to neutralization by authorized therapeutic human monoclonal antibodies (mAb) and is less …

Substantial neutralization escape by SARS-CoV-2 Omicron variants BQ. 1.1 and XBB. 1

J Miller, NP Hachmann, AY Collier… - … England Journal of …, 2023 - Mass Medical Soc
Substantial Neutralization Escape by SARS-CoV-2 Omicron Variants BQ.1.1 and XBB.1 |
NEJM Skip to main content NEJM Group Follow Us Facebook Twitter Instagram YouTube …

Household transmission of SARS-CoV-2 Omicron variant of concern subvariants BA. 1 and BA. 2 in Denmark

FP Lyngse, CT Kirkeby, M Denwood… - Nature …, 2022 - nature.com
Abstract SARS coronavirus 2 (SARS-CoV-2) continues to evolve and new variants emerge.
Using nationwide Danish data, we estimate the transmission dynamics of SARS-CoV-2 …