SARS-CoV-2 Omicron-B. 1.1. 529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19

EG Bentley, A Kirby, P Sharma, A Kipar, DF Mega… - BioRxiv, 2021 - biorxiv.org
ABSTRACT COVID-19 is a spectrum of clinical symptoms in humans caused by infection
with SARS-CoV-2. The B. 1.1. 529 Omicron variant is rapidly emerging and has been …

Diminished neutralization responses towards SARS-CoV-2 Omicron VoC after mRNA or vector-based COVID-19 vaccinations

H Jacobsen, M Strengert, H Maaß, MA Ynga Durand… - Scientific reports, 2022 - nature.com
SARS-CoV-2 variants accumulating immune escape mutations provide a significant risk to
vaccine-induced protection against infection. The novel variant of concern (VoC) Omicron …

Reduced sensitivity of commercial spike-specific antibody assays after primary infection with the SARS-CoV-2 Omicron variant

DN Springer, T Perkmann, CM Jani… - Microbiology …, 2022 - Am Soc Microbiol
ABSTRACT The SARS-CoV-2 Omicron variant is characterized by substantial changes in
the antigenic structure of the Spike (S) protein. Therefore, antibodies induced by primary …

Divergent SARS-CoV-2 Omicron–reactive T and B cell responses in COVID-19 vaccine recipients

CH GeurtsvanKessel, D Geers, KS Schmitz… - Science …, 2022 - science.org
The severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) Omicron
variant is spreading rapidly, even in vaccinated individuals, raising concerns about immune …

Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine

PS Arunachalam, Y Feng, U Ashraf, M Hu… - Science translational …, 2022 - science.org
Despite the remarkable efficacy of COVID-19 vaccines, waning immunity and the
emergence of SARS-CoV-2 variants such as Omicron represents a global health challenge …

SARS-CoV-2 Omicron strain exhibits potent capabilities for immune evasion and viral entrance

X Zhang, S Wu, B Wu, Q Yang, A Chen, Y Li… - Signal transduction and …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron strain (as known
as B. 1.1. 529) was identified in Botswana and South Africa in early November 2021 and …

Infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave

ST Tan, AT Kwan, I Rodríguez-Barraquer, BJ Singer… - Nature Medicine, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infections in
vaccinated individuals and reinfections in previously infected individuals have become …

Vaccine protection against the SARS-CoV-2 Omicron variant in macaques

A Chandrashekar, J Yu, K McMahan, C Jacob-Dolan… - Cell, 2022 - cell.com
The rapid spread of the SARS-CoV-2 Omicron (B. 1.1. 529) variant, including in highly
vaccinated populations, has raised important questions about the efficacy of current …

[HTML][HTML] Rapid decline in vaccine-boosted neutralizing antibodies against SARS-CoV-2 Omicron variant

KE Lyke, RL Atmar, CD Islas, CM Posavad… - Cell Reports …, 2022 - cell.com
The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
exhibits reduced susceptibility to vaccine-induced neutralizing antibodies, requiring a boost …

Omicron variant Spike-specific antibody binding and Fc activity are preserved in recipients of mRNA or inactivated COVID-19 vaccines

YC Bartsch, X Tong, J Kang, MJ Avendaño… - Science translational …, 2022 - science.org
The Omicron variant of SARS-CoV-2 has been shown to evade neutralizing antibodies
elicited by vaccination or infection. Despite the global spread of the Omicron variant, even …