[HTML][HTML] Infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave

ST Tan, AT Kwan, I Rodríguez-Barraquer, BJ Singer… - Nature Medicine, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infections in
vaccinated individuals and reinfections in previously infected individuals have become …

[HTML][HTML] Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant

M Schubert, F Bertoglio, S Steinke, PA Heine… - BMC medicine, 2022 - Springer
Background The COVID-19 pandemic is caused by the betacoronavirus SARS-CoV-2. In
November 2021, the Omicron variant was discovered and immediately classified as a …

[HTML][HTML] SARS-CoV-2 Omicron variant emerged under immune selection

CW Tan, WN Chia, F Zhu, BE Young… - Nature …, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant (B. 1.1. 529 lineage) escapes antibodies that
neutralize the ancestral virus. We tested human serum panels from participants with differing …

[HTML][HTML] Resistance of SARS-CoV-2 Omicron variant to convalescent and CoronaVac vaccine plasma

Y Wang, Y Ma, Y Xu, J Liu, X Li, Y Chen… - Emerging Microbes & …, 2022 - Taylor & Francis
Discussion There have been over 8.2 billion doses of SARS-CoV-2 vaccines administrated
in more than 4.3 billion persons around the world [1]. However, the emerging of the Omicron …

The altered entry pathway and antigenic distance of the SARS-CoV-2 Omicron variant map to separate domains of spike protein

TP Peacock, JC Brown, J Zhou, N Thakur, K Sukhova… - biorxiv, 2022 - biorxiv.org
At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …

[PDF][PDF] Vaccine protection against the SARS-CoV-2 Omicron variant in macaques

A Chandrashekar, J Yu, K McMahan, C Jacob-Dolan… - Cell, 2022 - cell.com
The rapid spread of the SARS-CoV-2 Omicron (B. 1.1. 529) variant, including in highly
vaccinated populations, has raised important questions about the efficacy of current …

Omicron variant Spike-specific antibody binding and Fc activity are preserved in recipients of mRNA or inactivated COVID-19 vaccines

YC Bartsch, X Tong, J Kang, MJ Avendaño… - Science translational …, 2022 - science.org
The Omicron variant of SARS-CoV-2 has been shown to evade neutralizing antibodies
elicited by vaccination or infection. Despite the global spread of the Omicron variant, even …

[HTML][HTML] Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA. 2

R Uraki, M Kiso, S Iida, M Imai, E Takashita, M Kuroda… - Nature, 2022 - nature.com
The recent emergence of SARS-CoV-2 Omicron (B. 1.1. 529 lineage) variants possessing
numerous mutations has raised concerns of decreased effectiveness of current vaccines …

[HTML][HTML] Mucosal boosting enhances vaccine protection against SARS-CoV-2 in macaques

K McMahan, F Wegmann, M Aid, M Sciacca, J Liu… - Nature, 2024 - nature.com
A limitation of current SARS-CoV-2 vaccines is that they provide minimal protection against
infection with current Omicron subvariants,, although they still provide protection against …

[HTML][HTML] Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

R Suzuki, D Yamasoba, I Kimura, L Wang, M Kishimoto… - Nature, 2022 - nature.com
The emergence of the Omicron variant of SARS-CoV-2 is an urgent global health concern. In
this study, our statistical modelling suggests that Omicron has spread more rapidly than the …