Abstract Interferon regulatory factor 2 (IRF-2) is known to play a pivotal role in the
development and progression of several malignancies. As a crucial member of interferon …

Background Since interferon regulatory factor (IRF) family functions in immune response to
viral infection, its role in colorectal cancer (CRC) has not been inspected before. This study …

Radiation is one of the main methods for the treatment of colorectal cancer (CRC) before or
after surgery. However, radiotherapy tolerance of patients with CRC is often a major …

Colorectal cancer (CRC) is one of the most common malignancies and causes of cancer-
related mortality worldwide. Cell proliferation and tumor metastasis as well as …

Colorectal cancer (CRC) is considered to be one of the most lethal cancer types globally,
and its recurrence is a major treatment challenge. Identifying the factors involved when …

Background Interferon regulatory factor 1 (IRF1) plays a role in the immune response,
cellular necrosis, DNA damage, and DNA repair, offering an attractive target for anticancer …

Abstract Interferon regulatory factor 1 (IRF1) has been suggested to act as a tumor
suppressor in human cancers. However, the clinical significance and biological function of …

Background Interferon regulatory factor 4 (IRF4) is a transcription factor from the IRF factor
family that exerts regulatory functions in the immune system and oncogenesis. However, the …

Purpose The interferon regulatory factor 2 (IRF-2) acted as a tumor suppressor. We
inspected IRF-2 as a predictor of prognosis in gastric cancer (GC) patients and tried to find …

Abstract IFN regulatory factor (IRF)-1 and IRF-2 are generally regarded as a tumor
suppressor and an oncoprotein, respectively. However, little is known about their expression …