[HTML][HTML] Decreased interferon regulatory factor 6 expression due to DNA hypermethylation predicts an unfavorable prognosis in clear cell renal cell carcinoma
Z Li, W Yang, J Qiu, H Xu, B Fan, K Li, J Zhou… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Emerging evidences have indicated that IRF6, as a member of the Interferon
regulatory factors (IRFs) family, plays important roles in a variety of tumors. However, the …
regulatory factors (IRFs) family, plays important roles in a variety of tumors. However, the …
[HTML][HTML] Interferon regulatory factor 4 correlated with immune cells infiltration could predict prognosis for patients with lung adenocarcinoma
X Li, S Zhai, J Zhang, D Zhang, S Wang, L Wang… - Frontiers in …, 2021 - frontiersin.org
Background Immune related interferon regulatory factor 4 (IRF4) is a member of the IRF
family, whereas the clinical significance and possible role of IRF4 in lung adenocarcinoma …
family, whereas the clinical significance and possible role of IRF4 in lung adenocarcinoma …
[HTML][HTML] Identification of IRF8 as an immune infiltration‐related biomarker in hepatocellular carcinoma by bioinformatics analysis
R Zhang, Y Guo, Z Liu, L Kong, C Li, L He, C Zhang… - MedComm, 2022 - ncbi.nlm.nih.gov
Dear Editor, Hepatocellular carcinoma (HCC), as a life-threatening disease, has become
one of the most common malignancies and one of the leading causes of cancer death …
one of the most common malignancies and one of the leading causes of cancer death …
Transcription factorIRX5 promotes hepatocellular carcinoma proliferation and inhibits apoptosis by regulating the p53 signalling pathway
L Zhu, L Dai, N Yang, M Liu, S Ma, C Li… - Cell Biochemistry …, 2020 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third
most frequent cause of cancer‐related death. The IRX5 transcription factor plays a different …
most frequent cause of cancer‐related death. The IRX5 transcription factor plays a different …
Restoration of IRF1-dependent anticancer effects by MEK inhibition in human cancer cells
N AbuSara, S Razavi, L Derwish, Y Komatsu, M Licursi… - Cancer Letters, 2015 - Elsevier
Interferon regulatory factor (IRF1) is a potent antiviral, antitumor and immune regulatory
protein. Recently, we found that activated Ras/MEK inhibits antiviral response by …
protein. Recently, we found that activated Ras/MEK inhibits antiviral response by …
Expression of IFITM3 in colorectal carcinoma and its clinical significance
K Cui, H Wang, S Zai, Y Feng - Zhonghua Zhong liu za zhi [Chinese …, 2015 - europepmc.org
Methods 213 patients with colon ademocarcinoma and 214 patients with colon adenoma
treated by surgery in our hospital from March 2008 to June 2010 were included in this study …
treated by surgery in our hospital from March 2008 to June 2010 were included in this study …
Single nucleotide polymorphisms in the IGF‐IRS pathway are associated with outcome in mCRC patients enrolled in the FIRE‐3 trial
M Schirripa, W Zhang, V Heinemann… - … journal of cancer, 2017 - Wiley Online Library
The Insulin‐like growth factor (IGF)/IGF‐receptor pathway with its scaffolding proteins Insulin
Receptor Substrate (IRS) 1 and IRS2 are crucial regulators of metabolism and progression …
Receptor Substrate (IRS) 1 and IRS2 are crucial regulators of metabolism and progression …
IFI6 predicts prognosis and promotes cell growth of human colorectal cancer
C Lv, M Li - Tropical Journal of Pharmaceutical Research, 2023 - ajol.info
Methods: Differentially-expressed genes were analyzed using a volcano plot. Metascape
and STRING were used for functional enrichment and protein-protein interaction network …
and STRING were used for functional enrichment and protein-protein interaction network …
[HTML][HTML] Interferon-inducible lncRNA IRF1-AS represses esophageal squamous cell carcinoma by promoting interferon response
J Huang, J Li, Y Li, Z Lu, Y Che, S Mao, Y Lei, R Zang… - Cancer Letters, 2019 - Elsevier
Interferons (IFNs) play crucial roles in the development and treatment of cancer. Long non-
coding RNAs (lncRNAs) are emerging molecules involved in cancer progression. Here, we …
coding RNAs (lncRNAs) are emerging molecules involved in cancer progression. Here, we …
Interferon regulatory factor 1 (IRF-1) activates anti-tumor immunity via CXCL10/CXCR3 axis in hepatocellular carcinoma (HCC)
Y Yan, L Zheng, Q Du, H Yazdani, K Dong, Y Guo… - Cancer letters, 2021 - Elsevier
Abstract Interferon regulatory factor 1 (IRF-1) is a tumor suppressor gene in cancer biology
with anti-proliferative and pro-apoptotic effect on cancer cells, however mechanisms of IRF-1 …
with anti-proliferative and pro-apoptotic effect on cancer cells, however mechanisms of IRF-1 …