Objective To evaluate the effectiveness of replacing dietary saturated fat with omega 6
linoleic acid, for the secondary prevention of coronary heart disease and death. Design …

Background—Previous studies on intake of linoleic acid (LA), the predominant n-6 fatty acid,
and coronary heart disease (CHD) risk have generated inconsistent results. We performed a …

Objective To examine the traditional diet-heart hypothesis through recovery and analysis of
previously unpublished data from the Minnesota Coronary Experiment (MCE) and to put …

Objective: To determine whether dietary supplementation with α linolenic acid (ALA) can
modify established and emerging cardiovascular risk markers. Design: Systematic review …

Objective To examine the associations between dietary intake and tissue biomarkers of
alpha linolenic acid (ALA) and risk of mortality from all causes, cardiovascular disease …

Objective Previous systematic reviews were not restricted to either primary or secondary
prevention trials, this study aimed to investigate the effects of reduced and/or modified fat …

Over the course of the twentieth century, there was a 20-fold increase in consumption of
vegetable oils resulting both from their increased availability and from recommendations to …

Background: Guidelines advocate changes in fatty acid consumption to promote
cardiovascular health. Purpose: To summarize evidence about associations between fatty …

Background Omega‐6 fats are polyunsaturated fats vital for many physiological functions,
but their effect on cardiovascular disease (CVD) risk is debated. Objectives To assess effects …

Our understanding of the cardiovascular disease (CVD) benefits of α-linolenic acid (ALA, 18:
3n–3) has advanced markedly during the past decade. It is now evident that ALA benefits …