[HTML][HTML] Magnesium as a new player in CKD: too little is as bad as too much?

N Hamano, H Komaba, M Fukagawa - Kidney International, 2017 - Elsevier
Vascular calcification is a serious complication of chronic kidney disease, but the current
therapeutic strategy is insufficient for preventing its progression. Magnesium is a potent …

Magnesium to prevent kidney disease–associated vascular calcification: crystal clear?

AD Ter Braake, MG Vervloet… - Nephrology Dialysis …, 2022 - academic.oup.com
Vascular calcification is a prognostic marker for cardiovascular mortality in chronic kidney
disease (CKD) patients. In these patients, magnesium balance is disturbed, mainly due to …

Magnesium and outcomes in patients with chronic kidney disease: focus on vascular calcification, atherosclerosis and survival

ZA Massy, TB Drüeke - Clinical kidney journal, 2012 - academic.oup.com
Patients with chronic kidney disease (CKD) have a high prevalence of vascular calcification,
and cardiovascular disease is the leading cause of death in this population. However, the …

[HTML][HTML] Magnesium and Vascular Calcification in Chronic Kidney Disease: Current Insights

SJ Zaslow, GH Oliveira-Paula, W Chen - International Journal of …, 2024 - mdpi.com
Magnesium (Mg) plays crucial roles in multiple essential biological processes. As the
kidneys are the primary organ responsible for maintaining the blood concentration of Mg …

Dietary magnesium supplementation inhibits abdominal vascular calcification in an experimental animal model of chronic kidney disease

NHJ Leenders, C Bos, T Hoekstra… - Nephrology Dialysis …, 2022 - academic.oup.com
Background Vascular calcification is a key process involved in cardiovascular morbidity and
mortality in patients with chronic kidney disease (CKD). Magnesium supplementation may …

The effect of magnesium supplementation on vascular calcification in CKD: a randomized clinical trial (MAGiCAL-CKD)

I Bressendorff, D Hansen, M Schou… - Journal of the …, 2023 - journals.lww.com
Background Elevated levels of serum magnesium are associated with lower risk of
cardiovascular events in patients with CKD. Magnesium also prevents vascular calcification …

Magnesium and progression of chronic kidney disease: benefits beyond cardiovascular protection?

Y Sakaguchi, T Hamano, Y Isaka - Advances in chronic kidney disease, 2018 - Elsevier
Experimental and clinical studies have demonstrated that magnesium deficiency leads to
hypertension, insulin resistance, and endothelial dysfunction, and is associated with an …

The effect of magnesium supplementation on vascular calcification in chronic kidney disease—A randomised clinical trial (MAGiCAL-CKD): Essential study design and …

I Bressendorff, D Hansen, M Schou, C Kragelund… - BMJ open, 2017 - bmjopen.bmj.com
Introduction Chronic kidney disease (CKD) is associated with an increased risk of
cardiovascular disease and mortality, which is thought to be caused by increased propensity …

Magnesium in chronic kidney disease: unanswered questions

DM Spiegel - Blood purification, 2011 - karger.com
Background: Magnesium ion is critical for life and is integrally involved in cellular function
and a key component of normal bone mineral. In health, the kidneys, gastrointestinal tract …

[HTML][HTML] Magnesium in CKD: more than a calcification inhibitor?

J Floege - Journal of nephrology, 2015 - Springer
Magnesium fulfils important roles in multiple physiological processes. Accordingly, a tight
regulation of magnesium homeostasis is essential. Dysregulated magnesium serum levels …