[HTML][HTML] Neuroinflammation, energy and sphingolipid metabolism biomarkers are revealed by metabolic modeling of autistic brains
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders generally characterized by repetitive behaviors and difficulties in communication …
disorders generally characterized by repetitive behaviors and difficulties in communication …
Untargeted metabolomics reveals hepatic metabolic disorder in the BTBR mouse model of autism and the significant role of liver in autism
C Cao, D Wang, M Zou, C Sun… - Cell Biochemistry and …, 2023 - Wiley Online Library
Autism spectrum disorder (ASD) is a neurodevelopmental disorder, and the etiology is
unknown. Metabolic dysfunction is present in patients with ASD. In the current study …
unknown. Metabolic dysfunction is present in patients with ASD. In the current study …
Targeted metabolomics highlights perturbed metabolism in the brain of autism spectrum disorder sufferers
Introduction Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders
characterized by deficiencies in social interactions and communication, combined with …
characterized by deficiencies in social interactions and communication, combined with …
Untargeted metabolomic analysis reveals the metabolic disturbances and exacerbation of oxidative stress in the cerebral cortex of a BTBR mouse model of Autism
C Cao, Q Li, Y Chen, M Zou, C Sun, X Li… - Journal of Molecular …, 2023 - Springer
The etiology and pathology of autism spectrum disorders (ASDs) are still poorly understood,
which largely limit the treatment and diagnosis of ASDs. Emerging evidence supports that …
which largely limit the treatment and diagnosis of ASDs. Emerging evidence supports that …
[HTML][HTML] A Computational Framework for Studying Gut-Brain Axis in Autism Spectrum Disorder
Introduction The integrity of the intestinal epithelium is crucial for human health and is
harmed in autism spectrum disorder (ASD). An aberrant gut microbial composition resulting …
harmed in autism spectrum disorder (ASD). An aberrant gut microbial composition resulting …
Parsing the heterogeneity of brain metabolic disturbances in autism spectrum disorder
J O'Neill, R Bansal, S Goh, M Rodie, S Sawardekar… - Biological …, 2020 - Elsevier
Background Despite rising prevalence of autism spectrum disorder (ASD), its brain bases
remain uncertain. Abnormal levels of N-acetyl compounds, glutamate+ glutamine, creatine+ …
remain uncertain. Abnormal levels of N-acetyl compounds, glutamate+ glutamine, creatine+ …
[HTML][HTML] Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism
DA Rossignol, RE Frye - Frontiers in physiology, 2014 - frontiersin.org
Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental
disorders that are defined solely on the basis of behavioral observations. Therefore, ASD …
disorders that are defined solely on the basis of behavioral observations. Therefore, ASD …
Genome-scale metabolic modelling predicts biomarkers and therapeutic targets for neuropsychiatric disorders
STR Moolamalla, PK Vinod - Computers in Biology and Medicine, 2020 - Elsevier
Distinguishing neuropsychiatric disorders is challenging due to the overlap in symptoms and
genetic risk factors. People suffering from these disorders face personal and professional …
genetic risk factors. People suffering from these disorders face personal and professional …
[HTML][HTML] Metabolomic signatures of autism spectrum disorder
Autism Spectrum Disorder (ASD) is associated with many variations in metabolism, but the
ex-act correlates of these metabolic disturbances with behavior and development and their …
ex-act correlates of these metabolic disturbances with behavior and development and their …
[HTML][HTML] Novel systems modeling methodology in comparative microbial metabolomics: identifying key enzymes and metabolites implicated in autism spectrum …
C Heberling, P Dhurjati - International journal of molecular sciences, 2015 - mdpi.com
Autism spectrum disorders are a group of mental illnesses highly correlated with
gastrointestinal dysfunction. Recent studies have shown that there may be one or more …
gastrointestinal dysfunction. Recent studies have shown that there may be one or more …
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