The inflammatory response has an important role in the pathophysiology of diabetic
nephropathy that is contributed to by inflammatory mediators such as interleukin‐1 (IL‐1), IL …

Diabetic complication is comprised of a wide variety of pathophysiological factors involving
proinflammatory cytokines, adipokines, and oxidative stress, among others. Each of these …

The role of the pro-inflammatory cytokine IL-17 in the pathogenesis of numerous
inflammatory disorders is well-documented, but conflicting results are reported for its role in …

AIM: In order to clarify the importance of Interleukin (IL)-18 in the development of diabetic
nephropathy (DN), we evaluated the expressions of IL-18 in diabetic kidney. METHODS: We …

Diabetic nephropathy (DN) is one of the most lethal complications of diabetes mellitus with
metabolic disorders and chronic inflammation. Although the cytokine IL-22 was initially …

Diabetic vascular complication is a leading cause of diabetic nephropathy, a progressive
increase in urinary albumin excretion coupled with elevated blood pressure leading to …

Diabetic nephropathy (DN) is a leading cause of chronic kidney disease (CKD). Interleukin-6
(IL-6) signaling participates in inflammation responses central to the progression of DN …

Diabetic nephropathy (DN) is one of the most common complications of diabetes, and
currently the first end-stage renal disease worldwide. New strategies to treat DN using …

Diabetes is the leading cause of kidney failure, accounting for> 45% of new cases of
dialysis. Diabetic nephropathy is characterized by inflammation, fibrosis, and oxidant stress …

Increased mesangial expansion is one of the most characteristic histological changes in
diabetic nephropathy (DN). Although the pathogenesis of DN remains unclear, recent …