Under normal physiological conditions, the hepatocyte growth factor (HGF) and its receptor,
the MET transmembrane tyrosine kinase (cMET), are involved in embryogenesis …

The hepatocyte growth factor (HGF)/c‑Met signaling pathway results in cancer cell scattering
and invasion, and has been reported to participate in several types of cancer, including …

Hepatocyte growth factor (HGF) is a stromal‐derived cytokine that plays a crucial role in
invasion and metastasis of tumor cells through the interaction with HGF receptor, c‐Met …

The receptor of hepatocyte growth factor (HGF), c-met induces different physiological
responses in several cell types. Little is known about the role of HGF in exocrine pancreas …

Hepatocellular carcinoma (HCC) is the fifth most common cancer and is the second leading
cause of cancer death. Since the diagnosis of HCC is difficult, in many cases patients with …

Tumor–stroma interactions in hepatocellular carcinoma (HCC) are of key importance to
tumor progression. In this study, we show that HCC invasive cells produce high levels of …

Advanced hepatocellular carcinoma (HCC) is an important cause of cancer mortality.
Epithelial-mesenchymal transition (EMT) has been shown to be an important biological …

The intensive stromal reaction is one of characteristics of pancreatic exocrine carcinoma.
The mutual interaction between pancreatic cancer cells and orthotopic tumor-derived …

Crosstalk between carcinoma cells and host stromal cells such as fibroblasts has a great
deal of influence on the invasive and metastatic behavior of cancer cells. The oncogenic …

This review provides a comprehensive landscape of HGF/c-MET (hepatocyte growth factor
(HGF)/mesenchymal–epithelial transition factor (c-MET)) signaling pathway in cancers. First …