Review of treatment and therapeutic targets in brain arteriovenous malformation

P Pan, S Weinsheimer, D Cooke… - Journal of Cerebral …, 2021 - journals.sagepub.com
Brain arteriovenous malformations (bAVM) are an important cause of intracranial
hemorrhage (ICH), especially in younger patients. The pathogenesis of bAVM are largely …

Brain arteriovenous malformation modeling, pathogenesis, and novel therapeutic targets

W Chen, EJ Choi, CM McDougall, H Su - Translational stroke research, 2014 - Springer
Patients harboring brain arteriovenous malformation (bAVM) are at life-threatening risk of
rupture and intracranial hemorrhage (ICH). The pathogenesis of bAVM has not been …

Genetics and emerging therapies for brain arteriovenous malformations

L Scherschinski, R Rahmani, VM Srinivasan… - World neurosurgery, 2022 - Elsevier
Brain arteriovenous malformations (AVMs) are characterized by a high-pressure, low-
resistance vascular nidus created by direct shunting of blood from feeding arteries into …

Current concepts and perspectives on brain arteriovenous malformations: a review of pathogenesis and multidisciplinary treatment

T Sugiyama, G Grasso, F Torregrossa, M Fujimura - World neurosurgery, 2022 - Elsevier
Brain arteriovenous malformations (bAVMs) are unusual vascular pathologies characterized
by the abnormal aggregation of dilated arteries and veins in the brain parenchyma and for …

Epidemiology, genetics, pathophysiology, and prognostic classifications of cerebral arteriovenous malformations

A Ozpinar, G Mendez, AA Abla - Handbook of Clinical Neurology, 2017 - Elsevier
Arteriovenous malformations (AVMs) are vascular deformities involving fistula formation of
arterial to venous structures without an intervening capillary bed. Such anomalies can prove …

[图书][B] Intracranial arteriovenous malformations

PE Stieg, HH Batjer, D Samson - 2006 - books.google.com
Offering expert recommendations and selected color illustrations, this guide furnishes
readers with state-of-the-art information on the pathophysiology, diagnosis, evaluation, and …

An update on medications for brain arteriovenous malformations

DMS Raper, EA Winkler, WC Rutledge, DL Cooke… - …, 2020 - journals.lww.com
Despite a variety of treatment options for brain arteriovenous malformations (bAVMs), many
lesions remain challenging to treat and present significant ongoing risk for hemorrhage. In …

Emerging pathogenic mechanisms in human brain arteriovenous malformations: a contemporary review in the multiomics era

EA Winkler, MA Pacult, JS Catapano… - Neurosurgical …, 2022 - thejns.org
A variety of pathogenic mechanisms have been described in the formation, maturation, and
rupture of brain arteriovenous malformations (bAVMs). While the understanding of bAVMs …

[HTML][HTML] Recent advances in basic research for brain arteriovenous malformation

L Barbosa Do Prado, C Han, SP Oh, H Su - International journal of …, 2019 - mdpi.com
Arteriovenous malformations (AVMs) are abnormal connections of vessels that shunt blood
directly from arteries into veins. Rupture of brain AVMs (bAVMs) can cause life-threatening …

Cerebral arteriovenous malformations. Part 1: cellular and molecular biology

P Moftakhar, JS Hauptman, D Malkasian… - Neurosurgical focus, 2009 - thejns.org
Object The scientific understanding of the nature of arteriovenous malformations (AVMs) in
the brain is evolving. It is clear from current work that AVMs can undergo a variety of …