Efficacy and tolerability of lovastatin in 459 African-Americans with hypercholesterolemia

ML Prisant, M Downton, LO Watkins… - The American journal of …, 1996 - Elsevier
A paucity of substantive data from clinical drug trials is available specifically evaluating the
effects of therapy for hypercholesterolemia in African-Americans, even though a substantial …

The efficacy of lovastatin in lowering cholesterol in African Americans with primary hypercholesterolemia

RL Fong, HJ Ward - The American journal of medicine, 1997 - Elsevier
PURPOSE: To evaluate the efficacy of lovastatin in African Americans (AA) diagnosed with
primary hypercholesterolemia. PATIENTS AND METHODS: Forty-seven AA patients from the …

Expanded clinical evaluation of lovastatin (EXCEL) study: design and patient characteristics of a double-blind, placebo-controlled study in patients with moderate …

RH Bradford, CL Shear, AN Chremos… - The American journal of …, 1990 - Elsevier
The randomized, double-blind, placebo-controlled trial described in this report was
undertaken to clarify the dose-response relation of lovastatin therapy to lipid-modifying …

Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: two-year efficacy and safety follow-up

RH Bradford, CL Shear, AN Chremos… - The American journal of …, 1994 - Elsevier
Abstract The Expanded Clinical Evaluation of Lovastatin study, a randomized, double-blind,
placebo-and diet-controlled multicenter trial, evaluated the efficacy and tolerability of …

Efficacy and tolerability of lovastatin in a six-month study: analysis by gender, age and hypertensive status

WB Kannel, RB D'Agostino, M Stepanians… - The American journal of …, 1990 - Elsevier
This study reports the results of a 6-month, open-label multicenter study of the efficacy and
tolerability of lovastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase …

A multicenter comparative trial of lovastatin and pravastatin in the treatment of hypercholesterolemia

Lovastatin Pravastatin Study Group - The American Journal of …, 1993 - Elsevier
A randomized, controlled, double-blind trial in 672 hypercholesterolemic patients evaluated
the efficacy and safety profile of lovastatin and pravastatin across their usually …

Expanded clinical evaluation of lovastatin (EXCEL) study results: IV. Additional perspectives on the tolerability of lovastatin

CA Dujovne, AN Chremos, JL Pool, H Schnaper… - The American journal of …, 1991 - Elsevier
This randomized, double-blind, multicenter, diet-and-placebo-controlled study was designed
to clarify the dose-response relationship of lovastatin therapy to lipid-modifying efficacy and …

Expanded clinical evaluation of lovastatin (EXCEL) study results: III. Efficacy in modifying lipoproteins and implications for managing patients with moderate …

RH Bradford, CL Shear, AN Chremos… - The American journal of …, 1991 - Elsevier
In the multicenter, double-blind EXCEL (Expanded Clinical Evaluation of Lovastatin) study
the efficacy of lovastatin in modifying plasma lipids and lipoproteins in 8,245 participants …

Comparison of efficacy and safety of rosuvastatin versus atorvastatin in African-American patients in a six-week trial

KC Ferdinand, LT Clark, KE Watson, RC Neal… - The American journal of …, 2006 - Elsevier
The lipid-modifying effects of statin therapy in hypercholesterolemic African-Americans have
not been well characterized. This study compared the efficacy and safety of rosuvastatin and …

Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: I. Efficacy in modifying plasma lipoproteins and adverse event profile in 8245 patients with …

RH Bradford, CL Shear, AN Chremos… - Archives of internal …, 1991 - jamanetwork.com
In the Expanded Clinical Evaluation of Lovastatin (EXCEL) Study, a multicenter, double-
blind, diet-and placebo-controlled trial, we evaluated the efficacy and safety of lovastatin in …