Understanding the redox biology of selenium in the search of targeted cancer therapies
Selenium (Se) is an essential trace nutrient required for optimal human health. It has long
been suggested that selenium has anti-cancer properties. However, clinical trials have …
been suggested that selenium has anti-cancer properties. However, clinical trials have …
Selenium in oncology: from chemistry to clinics
O Micke, L Schomburg, J Buentzel, K Kisters… - Molecules, 2009 - mdpi.com
The essential trace element selenium, which is a crucial cofactor in the most important
endogenous antioxidative systems of the human body, is attracting more and more the …
endogenous antioxidative systems of the human body, is attracting more and more the …
Selenium or no selenium-that is the question in tumor patients: a new controversy
R Muecke, L Schomburg, J Buentzel… - Integrative Cancer …, 2010 - journals.sagepub.com
The essential trace element selenium, which is a crucial cofactor in the most important
endogenous antioxidative systems of the human body, is attracting more attention from both …
endogenous antioxidative systems of the human body, is attracting more attention from both …
Redox-active selenium compounds—From toxicity and cell death to cancer treatment
Selenium is generally known as an antioxidant due to its presence in selenoproteins as
selenocysteine, but it is also toxic. The toxic effects of selenium are, however, strictly …
selenocysteine, but it is also toxic. The toxic effects of selenium are, however, strictly …
Selenium and cancer stem cells
G Murdolo, D Bartolini, C Tortoioli, M Piroddi… - Advances in Cancer …, 2017 - Elsevier
Selenium (Se) is an essential micronutrient that functions as “redox gatekeeper” and
homeostasis factor of normal and cancer cells. Epidemiology and experimental studies, in …
homeostasis factor of normal and cancer cells. Epidemiology and experimental studies, in …
[HTML][HTML] Selenium stimulates the antitumour immunity: Insights to future research
Selenium is an essential trace element for regulating immune functions through redox-
regulating activity of selenoproteins (eg glutathione peroxidase), protecting immune cells …
regulating activity of selenoproteins (eg glutathione peroxidase), protecting immune cells …
Selenium compounds as therapeutic agents in cancer
AP Fernandes, V Gandin - Biochimica et Biophysica Acta (BBA)-General …, 2015 - Elsevier
Background With cancer cells encompassing consistently higher production of reactive
oxygen species (ROS) and with an induced antioxidant defense to counteract the increased …
oxygen species (ROS) and with an induced antioxidant defense to counteract the increased …
Selenium and cancer: from prevention to treatment
J Brozmanova - Klinicka onkologie: casopis Ceske a Slovenske …, 2011 - europepmc.org
Selenium (Se) is an essential dietary component for all animals, including human beings,
that is regarded as a protective agent against cancer. Although the mode of its anticancer …
that is regarded as a protective agent against cancer. Although the mode of its anticancer …
Therapeutic benefits of selenium in hematological malignancies
Supplementing chemotherapy and radiotherapy with selenium has been shown to have
benefits against various cancers. This approach has also been shown to alleviate the side …
benefits against various cancers. This approach has also been shown to alleviate the side …
Selenium and selenocysteine: roles in cancer, health, and development
DL Hatfield, PA Tsuji, BA Carlson… - Trends in biochemical …, 2014 - cell.com
The many biological and biomedical effects of selenium are relatively unknown outside the
selenium field. This fascinating element, initially described as a toxin, was subsequently …
selenium field. This fascinating element, initially described as a toxin, was subsequently …