First-, Second-, and Third-Generation Radiolabeled Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Positron Emission Tomography: State of the Art, a …
MMA Sidrak, MS De Feo, V Frantellizzi… - Cancer Biotherapy & …, 2023 - liebertpub.com
Introduction: Lung cancer (LC) is a leading cause of death among men and women, with
non-small cell LC (NSCLC) accounting for a substantial portion of the histopathological …
non-small cell LC (NSCLC) accounting for a substantial portion of the histopathological …
[HTML][HTML] Positron emission tomography-computed tomography in the management of lung cancer: An update
P Sharma, H Singh, S Basu… - South Asian journal of …, 2013 - ncbi.nlm.nih.gov
This communication presents an update on the current role of positron emission tomography-
computed tomography (PET-CT) in the various clinical decision-making steps in lung …
computed tomography (PET-CT) in the various clinical decision-making steps in lung …
The development of positron emission tomography tracers for in vivo targeting the kinase domain of the epidermal growth factor receptor
A Högnäsbacka, AJ Poot, DJ Vugts… - Pharmaceuticals, 2022 - mdpi.com
Multiple small molecule PET tracers have been developed for the imaging of the epidermal
growth factor receptor (EGFR). These tracers target the tyrosine kinase (TK) domain of the …
growth factor receptor (EGFR). These tracers target the tyrosine kinase (TK) domain of the …
A PET imaging approach for determining EGFR mutation status for improved lung cancer patient management
X Sun, Z Xiao, G Chen, Z Han, Y Liu, C Zhang… - Science translational …, 2018 - science.org
Tumor heterogeneity and changes in epidermal growth factor receptor (EGFR) mutation
status over time challenge the design of effective EGFR tyrosine kinase inhibitor (TKI) …
status over time challenge the design of effective EGFR tyrosine kinase inhibitor (TKI) …
Molecular imaging for detection of sensitivity and resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer
Advancing knowledge of non-small cell lung cancer (NSCLC) has provided new treatment
options based on the specific gene alterations found in individual tumors. The presence of …
options based on the specific gene alterations found in individual tumors. The presence of …
Current progress and quality of radiomic studies for predicting EGFR mutation in patients with non-small cell lung cancer using PET/CT images: a systematic review
M Abdurixiti, M Nijiati, R Shen, Q Ya… - The British Journal of …, 2021 - academic.oup.com
Objectives: To assess the methodological quality of radiomic studies based on positron
emission tomography/computed tomography (PET/CT) images predicting epidermal growth …
emission tomography/computed tomography (PET/CT) images predicting epidermal growth …
Positron emission tomography‐computed tomography on predicting the efficacy of targeted therapy for lung adenocarcinoma
X Rong, X Cai, R Li, J Chen, Q Wang, C You… - Thoracic …, 2014 - Wiley Online Library
Background In this study, positron emission tomography‐computed tomography (PET‐CT)
was used to monitor the maximal standard uptake value (SUV max) in advanced lung …
was used to monitor the maximal standard uptake value (SUV max) in advanced lung …
[HTML][HTML] Experimental results and related clinical implications of PET detection of epidermal growth factor receptor (EGFr) in cancer
MA Pantaleo, M Nannini, A Maleddu, S Fanti, C Nanni… - Annals of oncology, 2009 - Elsevier
The epidermal growth factor receptor (EGFr) is one of the most studied molecules as a target
for cancer therapy. Over these last few years, several studies attempting to identify predictive …
for cancer therapy. Over these last few years, several studies attempting to identify predictive …
Molecular imaging of epidermal growth factor receptor expression–activity at the kinase level in tumors with positron emission tomography
JG Gelovani - Cancer and Metastasis Reviews, 2008 - Springer
Because of the importance of epidermal growth factor receptor (EGFR) signaling pathway in
oncogenesis, maintenance, and progression of different types of tumors, there has been an …
oncogenesis, maintenance, and progression of different types of tumors, there has been an …
[HTML][HTML] Radiolabeled EGFR TKI as predictive imaging biomarkers in NSCLC patients–an overview
E Van De Stadt, M Yaqub, AA Jahangir… - Frontiers in …, 2022 - frontiersin.org
Non-small cell lung cancer (NSCLC) has one of the highest cancer-related mortality rates
worldwide. In a subgroup of NSCLC, tumor growth is driven by epidermal growth factor …
worldwide. In a subgroup of NSCLC, tumor growth is driven by epidermal growth factor …
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