IN recent years major advances have occurred in the understanding and treatment of
cardiac arrhythmias. Epidemiologic studies including the use of ambulatory ECG monitoring …

Antiarrhythmic drugs are among medicine's most challenging to understand. Although
research in recent years has improved our understanding of the cellular mechanisms of …

Most antiarrhythmic drugs are potent compounds with a relatively narrow therapeutic index.
When prescribed judiciously, they can have a key role in enhancing or prolonging the lives …

Despite the emergence of several forms of nonpharmacologic therapy for cardiac
arrhythmias, antiarrhythmic drugs continue to play an important role in the management of …

THE APPROACH to the management of disorders of cardiac rhythm has undergone major
changes in the last ten years. 1, 2 The early experience with surgery and with pacemakers …

CASE STUDY ensuing month, she continues to have intermittent palpitations and fatigue.
Continuous ECG recording over a 48-hour period documents paroxysms of atrial fibrillation …

Cardiac arrhythmias occur in approximately 5.3% of the population and contribute
substantially to morbidity and mortality. Pharmacological therapy still remains the major …

In recent years, emphasis has been shifting away from the empirical to an increasingly
rational basis for the therapy of different cardiac arrhythmias in the clinic. During the last …

A 69-year-old retired teacher presents with a 1-month history of palpitations, intermittent
shortness of breath, and fatigue. She has a history of hypertension. An electrocardiogram …

I. Introduction....................................................................... 427 II. Etiology of Cardiac
Arrhythmias...................................................... 429 III. Antiarrhythmic Drug …