Repetitive model of mild traumatic brain injury produces cortical abnormalities detectable by magnetic resonance diffusion imaging, histopathology, and behavior

F Yu, DK Shukla, RC Armstrong, CM Marion… - Journal of …, 2017 - liebertpub.com
Noninvasive detection of mild traumatic brain injury (mTBI) is important for evaluating acute
through chronic effects of head injuries, particularly after repetitive impacts. To better detect …

[HTML][HTML] Repetitive mild traumatic brain injury in mice triggers a slowly developing cascade of long-term and persistent behavioral deficits and pathological changes

X Xu, M Cowan, F Beraldo, A Schranz… - Acta neuropathologica …, 2021 - Springer
We have previously reported long-term changes in the brains of non-concussed varsity
rugby players using magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) …

Repeated mild traumatic brain injury results in long-term white-matter disruption

V Donovan, C Kim, AK Anugerah… - Journal of Cerebral …, 2014 - journals.sagepub.com
Mild traumatic brain injury (mTBI) is an increasing public health concern as repetitive injuries
can exacerbate existing neuropathology and result in increased neurologic deficits. In …

Diffusion tensor imaging and white matter lesions at the subacute stage in mild traumatic brain injury with persistent neurobehavioral impairment

A Messé, S Caplain, G Paradot, D Garrigue… - Human brain …, 2011 - Wiley Online Library
Mild traumatic brain injury (mTBI) can induce long‐term behavioral and cognitive disorders.
Although the exact origin of these mTBI‐related disorders is not known, they may be the …

Acute white matter tract damage after frontal mild traumatic brain injury

JJ Herrera, K Bockhorst, S Kondraganti… - Journal of …, 2017 - liebertpub.com
Our understanding of mild traumatic brain injury (mTBI) is still in its infancy and to gain a
greater understanding, relevant animal models should replicate many of the features seen in …

[HTML][HTML] Traumatic brain injury augurs ill for prolonged deficits in the brain's structural and functional integrity following controlled cortical impact injury

AZ Mohamed, P Cumming, FA Nasrallah - Scientific reports, 2021 - nature.com
Previous neuroimaging studies in rodents investigated effects of the controlled cortical
impact (CCI) model of traumatic brain injury (TBI) within one-month post-TBI. This study …

Diffusion MRI abnormalities in adolescent rats given repeated mild traumatic brain injury

RC Wortman, A Meconi, KJ Neale… - Annals of clinical …, 2018 - Wiley Online Library
Objective Mild traumatic brain injury (mTBI) is a serious health concern in the adolescent
population. Repeated mTBI may result in more pronounced deficits, and has been …

Diffusion magnetic resonance imaging unveils the spatiotemporal microstructural gray matter changes following injury in the rodent brain

N Soni, AZ Mohamed, ND Kurniawan… - Journal of …, 2019 - liebertpub.com
Traumatic brain injury (TBI) is associated with gray and white matter alterations in brain
tissue. Gray matter alterations are not yet as well studied as those of the white matter …

Microstructural and microglial changes after repetitive mild traumatic brain injury in mice

S Robinson, JB Berglass, JL Denson… - Journal of …, 2017 - Wiley Online Library
Traumatic brain injury (TBI) is a major public health issue, with recently increased
awareness of the potential long‐term sequelae of repetitive injury. Although TBI is common …

Diffusion tensor imaging of the evolving response to mild traumatic brain injury in rats

WS Hoogenboom, TG Rubin, K Ye… - Journal of …, 2019 - journals.sagepub.com
Mild traumatic brain injury (mTBI), also known as concussion, is a serious public health
challenge. Although most patients recover, a substantial minority suffers chronic disability …