The 4-aminoquinolines, chloroquine or amodiaquine, have long been the drugs of choice for
treating uncomplicated, falciparum malaria in Africa, although resistance to them is now …

Objective To compare the efficacies against uncomplicated falciparum malaria of
chloroquine (CQ), amodiaquine (AQ), sulfadoxine–pyrimethamine (SP) and combinations of …

Resistance to chloroquine (CQ) requires its replacement as first-line therapy for
uncomplicated malaria in much of Africa. Combination therapy may improve efficacy and …

Increasing resistance to chloroquine necessitates the evaluation of other antimalarial
therapies in Africa. We compared the efficacies of amodiaquine (AQ), sulfadoxine …

The use of combinations of inexpensive drugs for the treatment of malaria in Africa has been
proposed as an interim policy while awaiting the widespread availability of more effective …

The study examined the efficacy of chloroquine (CQ), amodiaquine (AQ) and sulphadoxine–
pyrimethamine (SP) for the treatment of uncomplicated Plasmodium falciparum malaria in …

Chloroquine (CQ) remains the first-line treatment for uncomplicated malaria in much of
Africa despite the growing problem of resistance to this drug. Sulfadoxine-pyrimethamine …

In a southern border province of Lao PDR, we compared the efficacy of antimalarial drug
combinations in patients aged≥ 1 year with uncomplicated Plasmodium falciparum malaria …

While resistance to older antimalarials is increasingly common, newer antimalarials are still
not widely available or affordable in much of Africa. Older antimalarials used in combination …

A major problem in the control of malaria is the development of resistance, of the parasites to
the existing drugs and of the vectors to insecticides. With few new drugs in the pipeline, in an …