[PDF][PDF] The effect of alpha-mangostin in glucose level, cholesterol level and diameter of the islets of langerhans of STZ-induced diabetic mice

SA Husen, AANM Salamun, R Joko… - Proceedings of the …, 2018 - pdfs.semanticscholar.org
The increasing prevalence of Diabetes Mellitus (DM) worldwide is an issue of major socio-
economic concern. DM is a complex and a multifarious group of disorders that disturbs the …

Alpha mangostin and Xanthone activity on fasting blood glucose, insulin and langerhans Islet of langerhans in Alloxan induced diabetic mice

W Ratwita, EY Sukandar, IK Adnyana… - Pharmacognosy …, 2019 - phcogj.com
Objective: This research elaborated role of alpha mangostin and xanthone on fasting blood
glucose, insulin and langerhans islet in alloxan induced diabetic mice. Methods: Fasting …

[HTML][HTML] α-Mangostin mediated pharmacological modulation of hepatic carbohydrate metabolism in diabetes induced Wistar rat

V Kumar, PC Bhatt, G Kaithwas, M Rashid… - Beni-suef university …, 2016 - Elsevier
Garcinia mangostana L.(Fruit) has been commonly used as folklore drug in the treatment of
various types of diseases. The present experiment was designed to evaluate the potential …

Alpha-mangostin improves cardiac hypertrophy and fibrosis and associated biochemical parameters in high-fat/high-glucose diet and low-dose streptozotocin …

V Soetikno, A Murwantara, P Andini… - Journal of …, 2020 - Taylor & Francis
Purpose The aim of present study was to analyze the effect of alpha-mangostin on cardiac
hypertrophy and fibrosis and biochemical parameters in high-fat/high-glucose diet and low …

Alpha-mangostin improves insulin secretion and protects INS-1 cells from streptozotocin-induced damage

D Lee, YM Kim, K Jung, YW Chin, KS Kang - International Journal of …, 2018 - mdpi.com
Alpha (α)-mangostin, a yellow crystalline powder with a xanthone core structure, is isolated
from mangosteen (Garcinia mangostana), which is a tropical fruit of great nutritional value …

Hepatoprotective effect of gamma-mangostin for amelioration of impaired liver structure and function in streptozotocin-induced diabetic mice

SA Husen, D Winarni, ANM Ansori… - … Series: Earth and …, 2018 - iopscience.iop.org
The aim of this study was to investigate whether gamma-mangostin could reduce fasting
blood glucose, cholesterol, SGOT, SGPT, and also ameliorate damaged hepatocytes in …

[HTML][HTML] Mangosteen xanthone γ-mangostin exerts lowering blood glucose effect with potentiating insulin sensitivity through the mediation of AMPK/PPARγ

SP Chen, SR Lin, TH Chen, HS Ng, HS Yim… - Biomedicine & …, 2021 - Elsevier
Diabetes mellitus (DM) is concomitant with significant morbidity and mortality and its
prevalence is accumulative in worldwide. The conventional antidiabetic agents are known to …

Antioxidative activities of alpha-mangostin in high-fat/high-glucose diet and streptozotocin-induced insulin-resistant rodents

G Lazarus, S Alexander, GO Kusuma… - Journal of Applied …, 2020 - japsonline.com
Insulin resistance (IR), of which pathomechanism is mainly mediated by oxidative stress,
leads to impaired insulin secretion and multisystem damages. Recent evidence suggests …

The metabolic and molecular mechanisms of α‑mangostin in cardiometabolic disorders

OD John, AT Mushunje… - International …, 2022 - spandidos-publications.com
Abstract α‑mangostin is a xanthone predominantly encountered in Garcinia mangostana.
Extensive research has been carried out concerning the effects of this compound on various …

Antioxidant activity assay of alpha-mangostin for amelioration of kidney structure and function in diabetic mice

SA Husen, F Khaleyla, ANM Ansori… - … of Climate Change …, 2017 - atlantis-press.com
This research was aimed to investigate that alpha-mangostin compound derived from
mangosteen pericarp able to reduce blood urea nitrogen (BUN), plasma creatinine, also for …