Obesity and diabetes are strongly associated not only with fatty liver but also cognitive
dysfunction. Moreover, their presence, particularly in midlife, is recognized as a risk factor for …

Aim: Poor nutritional effect of junk food induces injuries to the liver and the brain but still
most of the developing nations survive on these diets to compensate for the fast-paced …

Heavy alcohol consumption is a known risk factor for various forms of dementia and the
development of Alzheimer's disease (AD). In this work, we investigated how intragastric …

Non-alcoholic fatty liver disease (NAFLD), the leading cause of chronic liver disease, is
associated with cognitive decline in middle-aged adults, but the mechanisms underlying this …

Background Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease afflicting
about one third of the world's population and 30% of the US population. It is induced by …

Background Obesity and diabetes are well-established risk factors of Alzheimer's disease
(AD). In the brains of patients with AD and model mice, diabetes-related factors have been …

Alzheimer's disease (AD) is an aging-dependent, irreversible neurodegenerative disorder
and the most common cause of dementia. The prevailing AD hypothesis points to the central …

Alzheimer's disease (AD) is the most common form of dementia. Obesity in middle age
increases AD risk and severity, which is alarming given that obesity prevalence peaks at …

Background Non-alcoholic fatty liver disease (NAFLD) is a prevalent risk factor for cognitive
impairment. Cerebral amyloid-β (Aβ) accumulation, as an important pathology of cognitive …

Introduction It has been suggested that obesity may influence Alzheimer's disease (AD)
pathogenesis, yet the numerous publications on this topic have inconsistent results and …