West syndrome: a review and guide for paediatricians

R D'Alonzo, D Rigante, E Mencaroni… - Clinical drug …, 2018 - Springer
West syndrome (WS), also known as infantile spasms, occurs in infancy with a peak
between 4 and 7 months. Spasms, neurodevelopmental regression and hypsarrhythmia on …

The treatment of West syndrome: a Cochrane review of the literature to December 2000

E Hancock, JP Osborne, P Milner - Brain and Development, 2001 - Elsevier
Background: West syndrome is an age dependant syndrome, which includes a peculiar type
of epileptic seizure (infantile spasms), usually hypsarrhythmia and in the majority …

[HTML][HTML] Treatment and long term outcome in West syndrome: the clinical reality. A multicentre follow up study

L Lagae, H Verhelst, B Ceulemans, L De Meirleir… - Seizure, 2010 - Elsevier
We systematically reviewed the files of 51 infants presenting with infantile spasms and
hypsarrhythmia in order to study the initial treatment strategies and the long term outcome …

Efficacy of treatments for infantile spasms: a systematic review

JM Song, J Hahn, SH Kim… - Clinical …, 2017 - journals.lww.com
Objectives West syndrome (also known as infantile spasm because of its main seizure type)
is a rare form of epilepsy that begins during early infancy. Recent guidelines and reviews on …

Adrenocorticotropic hormone for the treatment of West Syndrome in children

NA Shumiloff, WM Lam… - Annals of …, 2013 - journals.sagepub.com
OBJECTIVE To review the current literature on the efficacy and safety of low-versus high-
dose adrenocorticotropic hormone (ACTH) regimens, low-dose ACTH regimens, and …

Infantile spasms syndrome, West syndrome and related phenotypes: what we know in 2013

P Pavone, P Striano, R Falsaperla, L Pavone… - Brain and …, 2014 - Elsevier
The current spectrum of disorders associated to clinical spasms with onset in infancy is
wider than previously thought; accordingly, its terminology has changed. Nowadays, the …

Infantile spasms

EH Kossoff - The neurologist, 2010 - journals.lww.com
Background: Infantile spasms (West syndrome) is an epilepsy condition affecting 1 in 2000
infants. Perhaps no more worrisome neurologic disorder exists because of its frequent …

Improving outcomes in infantile spasms: role of pharmacotherapy

A Iyer, R Appleton - Pediatric Drugs, 2016 - Springer
Infantile spasms, and specifically within the context of West syndrome, is one of the most
common epileptic encephalopathies to occur in early infancy. Early recognition and …

[HTML][HTML] Long-term outcomes in patients with West syndrome: an outpatient clinical study

BT Güveli, Ö Çokar, N Dörtcan, G Benbir, V Demirbilek… - Seizure, 2015 - Elsevier
Purpose Nearly half of all patients with seizure onset in the first year of life suffer from West
syndrome (WS). The prognosis of epilepsy and psychosocial outcomes in children with WS …

Safety, tolerability, and effectiveness of oral zonisamide therapy in comparison with intramuscular adrenocorticotropic hormone therapy in infants with West syndrome

D Angappan, JK Sahu, P Malhi, P Singhi - european journal of paediatric …, 2019 - Elsevier
West syndrome is a distinct, infantile onset, epileptic encephalopathy, associated with poor
neurodevelopmental outcome. The present study was designed as a randomized, open …