Left ventricular remodeling after myocardial infarction: from physiopathology to treatment

SA Leancă, D Crișu, AO Petriș, I Afrăsânie, A Genes… - Life, 2022 - mdpi.com
Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …

Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies

S Frantz, MJ Hundertmark… - European heart …, 2022 - academic.oup.com
Most patients survive acute myocardial infarction (MI). Yet this encouraging development
has certain drawbacks: heart failure (HF) prevalence is increasing and patients affected tend …

Mechanisms of postinfarct left ventricular remodeling

BA French, CM Kramer - Drug Discovery Today: Disease Mechanisms, 2007 - Elsevier
Heart failure secondary to myocardial infarction (MI) remains a major source of morbidity
and mortality. Long-term outcome after MI can be largely be defined in terms of its impact on …

Postinfarct left ventricular remodelling: a prevailing cause of heart failure

A Galli, F Lombardi - Cardiology research and practice, 2016 - Wiley Online Library
Heart failure is a chronic disease with high morbidity and mortality, which represents a
growing challenge in medicine. A major risk factor for heart failure with reduced ejection …

Pharmacological modulation of cardiac remodeling after myocardial infarction

W Zhao, J Zhao, J Rong - Oxidative Medicine and Cellular …, 2020 - Wiley Online Library
Cardiac remodeling describes a series of structural and functional changes in the heart after
myocardial infarction (MI). Adverse post‐MI cardiac remodeling directly jeopardizes the …

Left ventricular remodeling in the post-infarction heart: a review of cellular, molecular mechanisms, and therapeutic modalities

JJ Gajarsa, RA Kloner - Heart failure reviews, 2011 - Springer
As more patients survive myocardial infarctions, the incidence of heart failure increases.
After an infarction, the human heart undergoes a series of structural changes, which are …

Remodeling in the ischemic heart: the stepwise progression for heart

JG Mill, I Stefanon, L Dos Santos… - Brazilian Journal of …, 2011 - SciELO Brasil
Coronary artery disease is the leading cause of death in the developed world and in
developing countries. Acute mortality from acute myocardial infarction (MI) has decreased in …

Ventricular remodeling in heart failure

MA Gaballa, S Goldman - Journal of cardiac failure, 2002 - Elsevier
This review briefly highlights the major mechanisms of left ventricular (LV) remodeling
following myocardial infarction in heart failure and presents novel strategies to limit infarct …

Adverse remodeling and reverse remodeling after myocardial infarction

AS Bhatt, AP Ambrosy, EJ Velazquez - Current cardiology reports, 2017 - Springer
Abstract Purpose of Review The purpose of this review it to summarize the current literature
on remodeling after myocardial infarction, inclusive of pathophysiological considerations …

Mechanisms contributing to cardiac remodelling

QQ Wu, Y Xiao, Y Yuan, ZG Ma, HH Liao, C Liu… - Clinical …, 2017 - portlandpress.com
Cardiac remodelling is classified as physiological (in response to growth, exercise and
pregnancy) or pathological (in response to inflammation, ischaemia, ischaemia/reperfusion …