Ratio of alpha 2-macroglobulin levels in cerebrospinal fluid and serum: an expression of neuroinflammation in acute disseminated encephalomyelitis

Y Suzuki, K Hashimoto, K Hoshi, H Ito, Y Kariya… - Pediatric Neurology, 2019 - Elsevier
Background Acute encephalitis and encephalopathy are life-threatening diseases in
children. However, no laboratory examinations are performed for their early diagnosis and …

Elevated levels of β2-microglobulin in cerebrospinal fluid in adult patients with viral encephalitis/meningitis

MZ Zhang, QG Shi, XY Xu, Y Qi, LJ Zhang, N Zhao… - Clinical …, 2024 - Elsevier
Background Increased cerebrospinal fluid (CSF) β2-microglobulin (β2-MG) values are
attributed to immune activation, lymphoid cell turnover and release of tissue destruction in …

Alpha2-macroglobulin as a promising biomarker for cerebral small vessel disease in acute ischemic stroke patients

T Nezu, N Hosomi, S Aoki, K Deguchi, H Masugata… - Journal of …, 2013 - Springer
Alpha2-macroglobulin is a protease inhibitor that enhances procoagulant properties via the
neutralization of plasmin, plasminogen activators and metalloproteinases. Additionally …

Human Alpha1-Microglobulin Levels in Neurological Disorders

Y Itoh, H Enomoto, K Takagi, T Obayashi… - European Neurology, 1983 - karger.com
The concentration of α 1-microglobulin (α 1-m) in sera and cerebrospinal fluids (CSF) was
measured in 121 patients with various neurological disorders. Using single radial …

Increased levels of β2-microglobulin, soluble interleukin-2 receptor, and soluble CD8 in patients with subacute sclerosing panencephalitis

PD Mehta, J Kulczycki, SP Mehta, W Sobczyk… - Clinical immunology and …, 1992 - Elsevier
We measured β2-microglobulin (β2-M), soluble interleukin-2 receptor (sIL-2R), and soluble
CD8 (sCD8) antigen levels in paired cerebrospinal fluid (CSF) and sera from patients with …

CSF α2-macroglobulin and C-reactive protein as aids to rapid diagnosis of acute bacterial meningitis

MA Virji, WF Diven, RH Kelly - Clinica chimica acta, 1985 - Elsevier
Abstract α 2-Macroglobulin (AMG) and C-reactive protein (CRP) levels in cerebrospinal fluid
(CSF) of patients with bacterial and aseptic meningitis have been analyzed by a rate …

Elevated cerebrospinal fluid β2-microglobulin levels in patients with neuromyelitis optica spectrum disorders

LJ Zhang, Y Qi, MQ Liu, SH Chang, CN Huang… - Multiple Sclerosis and …, 2021 - Elsevier
Abstract Cerebrospinal fluid (CSF) β2-microglobulin (β2-MG) levels elevated in patients with
multiple sclerosis (MS). We examined the levels of β2-MG in serum and cerebrospinal fluid …

Tracing immature myelin in acute disseminated encephalomyelitis

B Anlar, K Karli-Oğuz, OY Yurtyapan… - The Turkish Journal …, 2006 - turkjpediatr.org
Inherent abnormalities of myelin have been suggested in the pathogenesis of multiple
sclerosis (MS). We investigated myelin in acute disseminated encephalomyelitis (ADEM) …

[PDF][PDF] Relationship between severity of aseptic meningitis and cerebrospinal fluid cytokine levels

N Hikita, T Seto, K Yamashita, N Iritani… - … City Med J, 2015 - dlisv03.media.osaka-cu.ac.jp
Background Pediatricians sometimes see patients with severe aseptic meningitis and
prolonged fever or severe headache, or both. This condition generally has a good prognosis …

Cytokine and chemokine expression in CSF may differentiate viral and autoimmune NMDAR encephalitis in children

S Ygberg, Å Fowler… - Journal of Child …, 2016 - journals.sagepub.com
Childhood encephalitis is a potentially devastating condition with significant morbidity and
mortality. Researchers currently lack biomarkers for differentiating infectious encephalitis …