'Omics' and endocrine-disrupting chemicals—new paths forward

C Messerlian, RM Martinez, R Hauser… - Nature Reviews …, 2017 - nature.com
The emerging field of omics—large-scale data-rich biological measurements of the genome—
provides new opportunities to advance and strengthen research into endocrine-disrupting …

The regulation of endocrine-disrupting chemicals to minimize their impact on health

C Duh-Leong, MV Maffini, CD Kassotis… - Nature Reviews …, 2023 - nature.com
Endocrine-disrupting chemicals (EDCs) are substances generated by human industrial
activities that are detrimental to human health through their effects on the endocrine system …

Bridging the gap between academic research and regulatory health risk assessment of endocrine disrupting chemicals

A Beronius, A Hanberg, J Zilliacus, C Rudén - Current opinion in …, 2014 - Elsevier
Highlights•The use of academic research in risk assessment of EDCs needs to be
improved.•Regulatory risk assessment puts specific requirements on study design and …

A path forward in the debate over health impacts of endocrine disrupting chemicals

RT Zoeller, Å Bergman, G Becher, P Bjerregaard… - Environmental …, 2014 - Springer
Several recent publications reflect debate on the issue of “endocrine disrupting
chemicals”(EDCs), indicating that two seemingly mutually exclusive perspectives are being …

Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification

MA La Merrill, LN Vandenberg, MT Smith… - Nature Reviews …, 2020 - nature.com
Endocrine-disrupting chemicals (EDCs) are exogenous chemicals that interfere with
hormone action, thereby increasing the risk of adverse health outcomes, including cancer …

Key developments in endocrine disrupter research and human health

KP Phillips, WG Foster - Journal of toxicology and environmental …, 2008 - Taylor & Francis
Environmental etiologies involving exposures to chemicals that mimic endogenous
hormones are proposed for a number of adverse human health effects, including infertility …

Prenatal exposures to endocrine disrupting chemicals: The role of multi-omics in understanding toxicity

MH Rabotnick, J Ehlinger, A Haidari… - Molecular and Cellular …, 2023 - Elsevier
Endocrine disrupting chemicals (EDCs) are a diverse group of toxicants detected in
populations globally. Prenatal EDC exposures impact birth and childhood outcomes. EDCs …

Endocrine-disrupting chemicals and disease endpoints

C Ahn, EB Jeung - International journal of molecular sciences, 2023 - mdpi.com
Endocrine-disrupting chemicals (EDCs) have significant impacts on biological systems, and
have been shown to interfere with physiological systems, especially by disrupting the …

Evidence of the possible harm of endocrine-disrupting chemicals in humans: ongoing debates and key issues

DH Lee - Endocrinology and Metabolism, 2018 - synapse.koreamed.org
Evidence has emerged that endocrine-disrupting chemicals (EDCs) can produce adverse
effects, even at low doses that are assumed safe. However, systemic reviews and meta …

The history of endocrine-disrupting chemicals

PD Darbre - Current Opinion in Endocrine and Metabolic Research, 2019 - Elsevier
This mini-review offers a historical perspective on the emergence of endocrine disruption as
a multidisciplinary research area, encompassing studies from ecotoxicology to medicine and …