Fungi involved in lichen symbioses produce a large array of secondary metabolites that are
often diagnostic in the taxonomic delimitation of lichens. The most common lichen …

Lichenized and non-lichenized fungi produce a wide range of secondary metabolites. So far,
type I polyketide synthases (PKSs) are the suggested catalysts for the biosynthesis of lichen …

Lichens are fungi that form symbiotic partnerships with algae. Although lichens produce
diverse polyketides, difficulties in establishing and maintaining lichen cultures have …

Natural products (NPs) and their derivatives are a major contributor to modern medicine.
Historically, microorganisms such as bacteria and fungi have been instrumental in …

The depside and depsidone series compounds of polyketide origin accumulate in the
cortical or medullary layers of lichen thalli. Despite the taxonomic and ecological …

Lichen-forming fungi are unique organisms, producing biologically active metabolites with a
great variety of effects, including antibiotic, antimycobacterial, antiviral, anti-inflammatory …

Secondary metabolites play an important role in drug discovery. Lichens, in the first instance
the fungal symbiotic partner (referred to as mycobiont), produce a multitude of metabolites …

Lichens are symbionts of fungi and algae that produce diverse secondary metabolites with
useful properties. Little is known of lichen natural product biosynthesis because of the …

Lichens and most ascomycete fungi produce polyketide secondary metabolites often with
valuable biological activities. Their biosynthesis is primarily governed by large iterative …

The genes for polyketide synthases (PKSs), enzymes that assemble the carbon backbones
of many secondary metabolites, often cluster with other secondary pathway genes. We …