We read with interest the comment by Kremsner and Krishna on our paper published on this
Journal. The comment correctly points out that we documented an adequate clinical and …

Abstract Background The World Health Organization recommends quinine plus clindamycin
as first-line treatment of malaria in the first trimester of pregnancy and as a second-line …

Objective To compare the effectiveness of oral quinine with that of artemether-lumefantrine
in treating uncomplicated malaria in children. Design Randomised, open label effectiveness …

Background The treatment of falciparum malaria poses unique challenges in settings where
malaria transmission intensity is high because recurrent infections are common. These …

Background Artemether-lumefantrine (AL) was adopted as first-line treatment for
uncomplicated malaria in Kenya in 2006. Monitoring drug efficacy at regular intervals is …

Background Combination antimalarial therapy is recommended for the treatment of
uncomplicated falciparum malaria in Africa; however, some concerns about the safety and …

Antimalarial resistance threatens global malaria control efforts. The World Health
Organization (WHO) recommends routine antimalarial efficacy monitoring through a …

Background Triple antimalarial combination therapies combine potent and rapidly cleared
artemisinins or related synthetic ozonides, such as arterolane, with two, more slowly …

The emergence and spread of Plasmodium falciparum resistance to commonly used
antimalarials such as chloroquine and sulphadoxine/pyrimethamine poses major …

Background Between 2009 and 2012, malaria cases diagnosed in a Médecins sans
Frontières programme have increased fivefold in Baraka, South Kivu, Democratic Republic …