Pseudomonas aeruginosa Pangenome: Core and Accessory Genes of a Highly Resourceful Opportunistic Pathogen

KZ Abram, SR Jun, Z Udaondo - Pseudomonas aeruginosa: Biology …, 2022 - Springer
In this chapter, we leverage a novel approach to assess the seamless population structure of
Pseudomonas aeruginosa, using the full repertoire of genomes sequenced to date …

The Pseudomonas aeruginosa Pan-Genome Provides New Insights on Its Population Structure, Horizontal Gene Transfer, and Pathogenicity

L Freschi, AT Vincent, J Jeukens… - Genome biology and …, 2019 - academic.oup.com
The huge increase in the availability of bacterial genomes led us to a point in which we can
investigate and query pan-genomes, for example, the full set of genes of a given bacterial …

What It Takes to Be a Pseudomonas aeruginosa? The Core Genome of the Opportunistic Pathogen Updated

B Valot, C Guyeux, JY Rolland, K Mazouzi, X Bertrand… - PloS one, 2015 - journals.plos.org
Pseudomonas aeruginosa is an opportunistic bacterial pathogen able to thrive in highly
diverse ecological niches and to infect compromised patients. Its genome exhibits a mosaic …

Draft genomes of 12 host-adapted and environmental isolates of Pseudomonas aeruginosa and their positions in the core genome phylogeny

L Stewart, A Ford, V Sangal, J Jeukens… - Pathogens and …, 2014 - academic.oup.com
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen particularly
associated with the inherited disease cystic fibrosis (CF). Pseudomonas aeruginosa is well …

Phylogroup-specific variation shapes the clustering of antimicrobial resistance genes and defence systems across regions of genome plasticity in Pseudomonas …

J Botelho, L Tüffers, J Fuss, F Buchholz, C Utpatel… - …, 2023 - thelancet.com
Background Pseudomonas aeruginosa is an opportunistic pathogen consisting of three
phylogroups (hereafter named A, B, and C). Here, we assessed phylogroup-specific …

Pseudomonas aeruginosa Genomic Structure and Diversity

J Klockgether, N Cramer, L Wiehlmann… - Frontiers in …, 2011 - frontiersin.org
The Pseudomonas aeruginosa genome (G+ C content 65–67%, size 5.5–7 Mbp) is made up
of a single circular chromosome and a variable number of plasmids. Sequencing of …

Draft genome sequences of two Pseudomonas aeruginosa clinical isolates with different antibiotic susceptibilities

P Soares-Castro, D Marques, S Demyanchuk… - 2011 - Am Soc Microbiol
Pseudomonas aeruginosa is a primary cause of opportunistic infections. We have
sequenced and annotated the genomes of two P. aeruginosa clinical isolates evidencing …

The extensive set of accessory Pseudomonas aeruginosa genomic components

S Pohl, J Klockgether, D Eckweiler… - FEMS microbiology …, 2014 - academic.oup.com
Up to 20% of the chromosomal Pseudomonas aeruginosa DNA belong to the so-called
accessory genome. Its elements are specific for subgroups or even single strains and are …

Characterization of the core and accessory genomes of Pseudomonas aeruginosa using bioinformatic tools Spine and AGEnt

EA Ozer, JP Allen, AR Hauser - BMC genomics, 2014 - Springer
Background Pseudomonas aeruginosa is an important opportunistic pathogen responsible
for many infections in hospitalized and immunocompromised patients. Previous reports …

Genomic complexity and plasticity ensure Pseudomonas success

KP Rumbaugh - FEMS Microbiology Letters, 2014 - academic.oup.com
The first Pseudomonas genome was sequenced in 2000, and at 6.3 million base pairs, it
was, at the time, the largest bacterial genome ever sequenced (Stover et al., 2000). Not …