[HTML][HTML] Microfluidic three-dimensional cell culture of stem cells for high-throughput analysis
Although the recent advances in stem cell engineering have gained a great deal of attention
due to their high potential in clinical research, the applicability of stem cells for preclinical …
due to their high potential in clinical research, the applicability of stem cells for preclinical …
Three‐dimensional in vitro cell culture devices using patient‐derived cells for high‐throughput screening of drug combinations
Drug discovery using traditional animal models is often inefficient because test animal
models cannot accurately represent human responses, particularly in terms of toxicology …
models cannot accurately represent human responses, particularly in terms of toxicology …
Advances in microfluidic 3D cell culture for preclinical drug development
M Russo, CM Cejas, G Pitingolo - Progress in Molecular Biology and …, 2022 - Elsevier
Drug development is often a very long, costly, and risky process due to the lack of reliability
in the preclinical studies. Traditional current preclinical models, mostly based on 2D cell …
in the preclinical studies. Traditional current preclinical models, mostly based on 2D cell …
Microfluidic 3D cell culture: potential application for tissue-based bioassays
Current fundamental investigations of human biology and the development of therapeutic
drugs commonly rely on 2D monolayer cell culture systems. However, 2D cell culture …
drugs commonly rely on 2D monolayer cell culture systems. However, 2D cell culture …
Microfluidics‐based 3D cell culture models: Utility in novel drug discovery and delivery research
The implementation of microfluidic devices within life sciences has furthered the possibilities
of both academic and industrial applications such as rapid genome sequencing, predictive …
of both academic and industrial applications such as rapid genome sequencing, predictive …
Microengineering methods for cell-based microarrays and high-throughput drug-screening applications
Screening for effective therapeutic agents from millions of drug candidates is costly, time
consuming, and often faces concerns due to the extensive use of animals. To improve cost …
consuming, and often faces concerns due to the extensive use of animals. To improve cost …
Recent advances in microfluidic 3D cellular scaffolds for drug assays
Microfluidic technologies enable temporal and spatial control of cellular microenvironments
by mimicking the complex biological functions of normal cellular interactions, thus opening …
by mimicking the complex biological functions of normal cellular interactions, thus opening …
Stem cell culture and differentiation in microfluidic devices toward organ-on-a-chip
Microfluidic lab-on-a-chip provides a new platform with unique advantages to mimic
complex physiological microenvironments in vivo and has been increasingly exploited to …
complex physiological microenvironments in vivo and has been increasingly exploited to …
Microfluidic high-throughput 3D cell culture
High-throughput 3D microfluidic cell culture systems can be designed to model aspects of
human tissues and organs and may thus serve as non-clinical evaluation tools. They benefit …
human tissues and organs and may thus serve as non-clinical evaluation tools. They benefit …
Recent advances on cell culture platforms for in vitro drug screening and cell therapies: from conventional to microfluidic strategies
BD Cardoso, EMS Castanheira… - Advanced …, 2023 - Wiley Online Library
The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical
research based on biologically accurate screening approaches. Since establishing the 2D in …
research based on biologically accurate screening approaches. Since establishing the 2D in …