Blood Pressure Level Is Associated With Changes in Plasma Aβ1 –40 and Aβ1–42 Levels: A Cross-sectional Study Conducted in the Suburbs of Xi'an, China

M She, S Shang, N Hu, C Chen, L Dang… - Frontiers in Aging …, 2021 - frontiersin.org
Objectives: Amyloid-β (Aβ) deposition in the brain is the hallmark of Alzheimer's disease
(AD) pathology. Hypertension is a risk factor for AD, but the effects of hypertension on Aβ …

Blood pressure, dementia and Alzheimer's disease: the OPTIMA longitudinal study

G Razay, J Williams, E King, AD Smith… - Dementia and geriatric …, 2009 - karger.com
Abstract Background/Aims: Studies on the relation between blood pressure (BP), dementia
and Alzheimer's disease (AD) have yielded inconsistent results, showing an association with …

Impaired memory is more closely associated with brain beta-amyloid than leukoaraiosis in hypertensive patients with cognitive symptoms

EE Smith, A Muzikansky, CR McCreary, S Batool… - PLoS …, 2018 - journals.plos.org
Background Hypertension is the strongest modifiable risk factor for subcortical ischemic
changes and is also a risk factor for Alzheimer's dementia. We used neuroimaging to …

Tau mediates synergistic influence of vascular risk and Aβ on cognitive decline

WYW Yau, Z Shirzadi, HS Yang, AP Ikoba… - Annals of …, 2022 - Wiley Online Library
Objective Elevated vascular risk and beta‐amyloid (Aβ) burden have been synergistically
associated with cognitive decline in preclinical Alzheimer's disease (AD), although the …

Relationship between late-life hypertension, blood pressure, and Alzheimer's disease

YH Yang, CM Roe, JC Morris - American Journal of …, 2011 - journals.sagepub.com
Relationship between late-life hypertension and Alzheimer's disease (AD) remains less
clear. Both cross-sectional and longitudinal methods were used to examine whether systolic …

Blood pressure and Alzheimer's disease: A review of meta-analysis

O Saiz-Vazquez, A Puente-Martinez… - Frontiers in …, 2023 - frontiersin.org
Background Alzheimer's disease (AD) is a neurological disorder of unknown cause,
resulting in the death of brain cells. Identifying some of the modifiable risk factors for AD …

Systolic blood pressure is associated with increased brain amyloid load in mild cognitively impaired participants: Alzheimer's disease neuroimaging initiatives study

TV Fungwe, JS Ngwa, SP Johnson, JV Turner… - Dementia and geriatric …, 2023 - karger.com
Abstract Background: Cardiovascular disease (CVD), including elevated blood pressure
(BP), is known to promote Alzheimer's disease (AD) risk. Although brain amyloid load is a …

Long-term blood pressure variability across the clinical and biomarker spectrum of Alzheimer's disease

IJ Sible, DA Nation… - Journal of …, 2020 - content.iospress.com
Background: Elevated blood pressure is linked to cognitive impairment and Alzheimer's
disease (AD) biomarker abnormality. However, blood pressure levels vary over time. Less is …

Update on hypertension and Alzheimer's disease

I Skoog, D Gustafson - Neurological research, 2006 - Taylor & Francis
Several studies report that blood pressure is increased in victims of Alzheimer's disease
(AD) decades before the onset of the disease. Years before onset of Alzheimer's disease …

Distinct white matter changes associated with cerebrospinal fluid amyloid-β 1-42 and hypertension

OM Al-Janabi, CA Brown, AA Bahrani… - Journal of …, 2018 - content.iospress.com
Background: Alzheimer's disease (AD) pathology and hypertension (HTN) are risk factors for
development of white matter (WM) alterations and might be independently associated with …