Mid-life hypertension and cerebral hypoperfusion may be preclinical abnormalities in people
who later develop Alzheimer's disease. Although accumulation of amyloid-beta (Aβ) is …

Abstract Background. The differentiation of Alzheimer's disease (AD) from vascular dementia
(VaD) is hampered by clinical diagnostic criteria with disappointing sensitivity and specificity …

Background: Accumulation of amyloid-β (Aβ) and hyperphosphorylated tau (ptau)
accompany cerebral small vessel disease (CSVD) in the aging brain and in Alzheimer's …

Background A lot of attention has been paid to the relationship of blood pressure and
dementia because epidemiological research has reported conflicting evidence …

Identification of biomarkers for the early stages of Alzheimer's disease (AD) is an imperative
step in developing effective treatments. Cerebral blood flow (CBF) is a potential early …

Alzheimer's disease, the most common type of dementia among older adults, currently
cannot be prevented or effectively treated. Only a very small percentage of Alzheimer's …

Chronic hypertension, or high blood pressure, is the most prevalent vascular risk factor that
accelerates cognitive aging and increases risk for Alzheimer's disease and related …

(1) Background: The role of antihypertensives in Alzheimer's Disease (AD) prevention is
controversial. This case-control study aims to assess whether antihypertensive medication …

Objective Midlife vascular risk factors (MVRFs) are associated with incident dementia, as are
amyloid β (Aβ) deposition and neurodegeneration. Whether vascular and Alzheimer disease …

In this nationwide cohort study, we assessed the effects of hypertension burden and blood
pressure (BP) control on dementia in different age subgroups. From the Korean National …