Features of a number of important but poorly explained human clinical syndromes strongly
indicate a microbial etiology. In these syndromes, the failure of cultivation-dependent …

Diagnostic molecular methods have had a large effect on diagnosis and management of
infectious diseases. These tools have been developed in response to diagnostic methods …

A major aim of clinical microbiologists over the last century has been to demonstrate the
presence of pathogenic microorganisms in clinical or pathologic samples associated with …

As molecular techniques for identifying and detecting microorganisms in the clinical
microbiology laboratory have become routine, questions about the cost of these techniques …

Gene amplification and sequencing have led to the discovery of new pathogens as agents of
disease and have enabled us to better classify microorganisms from culture. Sequence …

IN recent years a large number of articles have appeared in clinical journals describing
contemporary molecular methods and their applications in clinical medicine. This review …

As more original molecular protocols and subsequent modifications are described in the
literature, it has become difficult for those not directly involved in the development of these …

Naturally emerging and deliberately released pathogens demand new detection strategies
to allow early recognition and containment. We describe a diagnostic system for rapid …

Identification of emerging bacterial pathogens generally results from a chain of events
involving microscopy, serology, molecular tools, and culture. Because of the spectacular …

Objective.—In this review, we will focus on recent molecular typing methods that can be
applied to different pathogens and assess their values and limitations. Background …