Reduced lung diffusing capacity for carbon monoxide (DLCO) at rest and increased
ventilation (⩒ E)-carbon dioxide output (⩒ CO2) during exercise are frequent findings in …

Emphysema distribution is associated with chronic obstructive pulmonary disease. It is,
however, unknown whether computed tomography (CT)-quantified emphysema distribution …

Purpose To evaluate the relationships between DL CO, and Quantitative CT (QCT)
measurements and visual assessment of pulmonary emphysema and to test the relative …

Rationale: Emphysema occurs in distinct pathologic patterns, but little is known about the
epidemiologic associations of these patterns. Standard quantitative measures of …

Rationale: Computed tomography (CT)-based lung density is used to quantitate the
percentage of emphysema-like lung (hereafter referred to as percent emphysema), but …

Objective The objective of this study was to determine the capability of quantitative
emphysema by computed tomography (CT) to assess pulmonary function impairment in a …

The aims of this study were to perform a longitudinal evaluation of the cross‐sectional area
(CSA) of small pulmonary vessels and the extent of emphysema measured on computed …

Background Previous work suggests that mild chronic obstructive pulmonary disease
(COPD) patients have greater lung dysfunction than previously appreciated from spirometry …

Background Decreased diffusing capacity of the lung for carbon monoxide (DLCO) is
associated with emphysema. DLCO is also related to decreased arterial oxygen tension …

Rationale: Vascular alteration of small pulmonary vessels is one of the characteristic
features of pulmonary hypertension in chronic obstructive pulmonary disease. The in vivo …