Objective We hypothesized that downregulation of the antioxidant thioredoxin system
contributes to oxidative stress in angiotensin II-induced hypertension. As oestrogen may …

Reactive oxygen species increase in the cardiovascular system during hypertension and in
response to angiotensin II. Because mitochondria contribute to reactive oxygen species …

As oxidative stress plays a crucial role in the development and pathogenesis of
hypertension, we analyzed the redox (reduction/oxidation) status in tissues from Wistar …

Oxidative stress is implicated in menopause-associated hypertension and cardiovascular
disease. The role of antioxidants in this process is unclear. We questioned whether the …

THIS FORUM ISSUE of Antioxidants & Redox Signaling highlights the role of reactive
oxygen species in hypertension. Although the association between free radicals and …

NADPH oxidase has been implicated in ANG II-induced oxidative stress and hypertension in
males; however, the contribution of oxidative stress to ANG II hypertension in females is …

Hypertension is frequently associated with oxidative stress caused by high production of
reactive oxygen species and compromised antioxidant defenses. Humans with essential …

Excessive oxidative stress is a major causative factor of endothelial dysfunction in
hypertension. As an endogenous pro-oxidant, thioredoxin-interacting protein (TXNIP) …

The aim of this study was to provide new insights into the role of angiotensin II and arterial
pressure in the regulation of antioxidant enzyme activities in a renovascular model of …

This study examines whether longitudinal antioxidant treatment initiated in prehypertensive
spontaneously hypertensive rats (SHR) can attenuate vascular oxidant stress and prevent …