Pharmacodynamics and tolerability of repository corticotropin injection in healthy human subjects: a comparison with intravenous methylprednisolone
R Lal, S Bell, R Challenger, V Hammock… - The Journal of …, 2016 - Wiley Online Library
Repository corticotropin injection (porcine adrenocorticotropic hormone [ACTH] analog) and
intravenous methylprednisolone (IVMP) are used to treat inflammatory conditions such as …
intravenous methylprednisolone (IVMP) are used to treat inflammatory conditions such as …
Comparison of Steroidogenic Exposure Following the Administration of Repository Corticotropin Injection With a Synthetic ACTH1‐24 Depot and Methylprednisolone …
X Wang, L Pham, N Poola, LR Brooks… - … Pharmacology in Drug …, 2021 - Wiley Online Library
The pharmacokinetics (PK) and pharmacodynamics (PD) of clinically relevant doses of
repository corticotropin injection (Acthar Gel) and synthetic ACTH1‐24 depot have not been …
repository corticotropin injection (Acthar Gel) and synthetic ACTH1‐24 depot have not been …
Pharmacokinetics and Pharmacodynamics of Repository Corticotropin Injection Compared With Synthetic ACTH1‐24 Depot and Methylprednisolone in Healthy …
N Poola, B Due, D Wright, LR Brooks… - … Pharmacology in Drug …, 2022 - Wiley Online Library
Repository corticotropin injection (RCI; Acthar Gel) is a naturally sourced complex mixture of
adrenocorticotropic hormone (ACTH) analogs and other pituitary peptides. This phase 1 …
adrenocorticotropic hormone (ACTH) analogs and other pituitary peptides. This phase 1 …
Clinical and economic evaluation of repository corticotropin injection: a narrative literature review of treatment efficacy and healthcare resource utilization for seven …
M Philbin, J Niewoehner, GJ Wan - Advances in Therapy, 2017 - Springer
Introduction Repository corticotropin injection (RCI; HP Acthar® Gel; Mallinckrodt
Pharmaceuticals Inc., Hampton, NJ) is a highly purified, prolonged-release porcine …
Pharmaceuticals Inc., Hampton, NJ) is a highly purified, prolonged-release porcine …
Results from a multicenter, randomized, double‐blind, placebo‐controlled study of repository corticotropin injection for multiple sclerosis relapse that did not …
D Wynn, L Goldstick, W Bauer, E Zhao… - CNS Neuroscience …, 2022 - Wiley Online Library
Abstract Introduction About 20%–35% of multiple sclerosis (MS) patients fail to respond to
high‐dose corticosteroids during a relapse. Repository corticotropin injection (RCI, Acthar® …
high‐dose corticosteroids during a relapse. Repository corticotropin injection (RCI, Acthar® …
Effects of repository corticotropin injection on medication use in patients with rheumatologic conditions: a claims data study
G Myung, WW Nelson… - Journal of Pharmacy …, 2017 - journals.sagepub.com
Background: Currently, specific studies identifying how repository corticotropin injection
(RCI) is used in rheumatologic conditions are lacking. This is a first step to familiarize the …
(RCI) is used in rheumatologic conditions are lacking. This is a first step to familiarize the …
A retrospective medical record review of utilization patterns and medical resource use associated with repository corticotropin injection among patients with …
WW Nelson, MJ Philbin, JR Gallagher, K Heap… - Rheumatology and …, 2017 - Springer
Introduction Repository corticotropin injection (RCI) has anti-inflammatory and immune-
modulatory effects and is approved for multiple indications, including several rheumatologic …
modulatory effects and is approved for multiple indications, including several rheumatologic …
Safety of repository corticotropin injection as an adjunctive therapy for the treatment of rheumatoid arthritis
R Fleischmann, DE Furst - Expert Opinion on Drug Safety, 2020 - Taylor & Francis
Introduction Disease-modifying antirheumatic drugs (DMARDs) have significantly improved
clinical symptoms and quality of life with reduced disease progression in many patients with …
clinical symptoms and quality of life with reduced disease progression in many patients with …
Characterization of the clinical evidence supporting repository corticotropin injection for FDA-approved indications: a scoping review
KA Tran, C Harrod, DN Bourdette… - JAMA internal …, 2022 - jamanetwork.com
Importance Repository corticotropin injection is an expensive medication that was approved
in 1952 for the treatment of many inflammatory conditions. The clinical evidence supporting …
in 1952 for the treatment of many inflammatory conditions. The clinical evidence supporting …
Real-world treatment patterns and outcomes from an electronic medical records database for patients with rheumatoid arthritis treated with repository corticotropin …
K Hayes, MP Panaccio, P Houston… - Open Access …, 2021 - Taylor & Francis
Purpose Repository corticotropin injection (RCI; Acthar® Gel) is a naturally sourced mixture
of adrenocorticotropic hormone analogs and other pituitary peptides that exerts anti …
of adrenocorticotropic hormone analogs and other pituitary peptides that exerts anti …