Endothelial dysfunction has been implicated as a key factor in the development of a wide
range of cardiovascular diseases, but its definition and mechanisms vary greatly between …

The endothelium enables communication between blood and tissues and is actively
involved in cardiovascular homeostasis. Endothelial dysfunction has been recognized as an …

Endothelial dysfunction is an early and persistent vascular abnormality in the evolution of
atherothrombotic disease. Risk factors for atherosclerosis promote an inflammatory oxidative …

The endothelium plays important roles in modulating vascular tone by synthesizing and
releasing a variety of endothelium-derived relaxing factors, including vasodilator …

Endothelial dysfunction (ED) in the setting of cardiovascular risk factors such as
hypercholesterolemia, hypertension, diabetes mellitus, chronic smoking as well as in …

Cardiovascular diseases (CVD), including heart and pathological circulatory conditions, are
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …

The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

The vascular endothelium not only is a single monolayer of cells between the vessel lumen
and the intimal wall, but also plays an important role by controlling vascular function and …

The vascular endothelium is involved in the release of various vasodilators, including nitric
oxide (NO), prostacyclin and endothelium-derived hyperpolarizing factor, as well as …

Introduction: Dysfunction of vessel endothelium is the first step in a complex and multi-
faceted process that eventually leads to initiation of the plaque, formation of atherosclerotic …