It has been reported that estrogen receptors (ERs) participate in carcinogenesis by directly
regulating NOD-like receptors (NLRs). However, the expression profiles of ERs and NLRs in …

Abstract Background The Wnt signaling pathway is a complex network of protein interactions
that functions most commonly in embryonic development and cancer, but is also involved in …

Epidemiologic studies reported that the prevalence of hereditary non-polyposis colon cancer
(HNPCC) in male is about 1.5-fold higher than that in female. Decreases in circulatory …

Colorectal cancer (CRC) is the predominant cause of cancer-related death worldwide,
because of the lack of effective therapeutic targets. Estrogen-related receptor gamma …

Wnt2 is implicated in various human cancers. However, it remains unknown how Wnt2 is
upregulated in human cancer and contributes to tumorigenesis. Here we found that Wnt2 is …

Colorectal cancer (CRC) is a heterogeneous disease with changes in the genetic and
epigenetic levels of various genes. The molecular assessment of CRC is gaining increasing …

Increasing evidence indicates that the NOD-like receptors (NLRs) family may act as critical
back-up defenses and provide synergistic responses when confronted with persistent …

Abstract Background Estrogen receptors (ERs) are thought to play an important role in non-
small cell lung cancer (NSCLC). However, the effect of ERs in NSCLC is still controversial …

Aberrant activation of beta-catenin/TCF signaling is one of the hallmarks of colon cancer. It is
of great interest to study the mechanism for the regulation of beta-catenin/TCF signaling. In …

Abstract Background Long non-coding RNAs (lncRNAs) have been identified to play an
important role in the development and progression of various tumors, including colorectal …