Animal models play a critical role in the study of acute respiratory distress syndrome (ARDS)
and ventilator-induced lung injury (VILI). One limitation has been the lack of a suitable …

Rationale It is well known that acute respiratory distress syndrome and ventilator induced
lung injury (VILI) are very heterogeneous conditions within the lungs. However, it is …

Although mechanical ventilation (MV) is a life-saving intervention for patients with acute
respiratory distress syndrome (ARDS), it can aggravate or cause lung injury, known as …

Background. Mechanical ventilation (MV) has the potential to initiate ventilator‐induced lung
injury (VILI). The pathogenesis of VILI has been primarily studied in animal models using …

Supportive mechanical ventilation is a necessary lifesaving treatment for acute respiratory
distress syndrome (ARDS). This intervention often leads to injury exacerbation by ventilator …

Mechanical ventilation is vital to the management of acute respiratory distress syndrome, but
it frequently leads to ventilator-induced lung injury (VILI). Understanding the …

Background Mechanical ventilation worsens acute respiratory distress syndrome, but this
secondary “ventilator-associated” injury is variable and difficult to predict. The authors aimed …

Background: Lung injury associated with the acute respiratory distress syndrome can be
exacerbated by improper mechanical ventilation creating a secondary injury known as …

This review focuses on the advances in the understanding of the pathophysiology of
ventilator-induced and acute lung injury that have been afforded by technological …

Mechanical ventilation is a life-saving therapy in several clinical situations, promoting gas
exchange and providing rest to the respiratory muscles. However, mechanical ventilation …