Rationale Attention is compromised in many psychiatric disorders, including attention-
deficit/hyperactivity disorder (ADHD). While dopamine and noradrenaline systems have …

Rationale The 5-choice serial reaction time task (5-CSRTT) is widely used to measure
rodent attentional functions. In humans, many attention studies in healthy and clinical …

Methods Here we present a series of experiments in rats that seeks to investigate the origins
of these key behavioral measures of attention in the 5-CSRTT. After an initial training in the 5 …

Background The 5-choice serial reaction time task (5-CSRTT) is an automated operant
conditioning task that measures rodent attention. The task allows the measurement of …

The rapid serial visual presentation (RSVP) task and continuous performance tasks (CPT)
are used to assess attentional impairments in patients with psychiatric and neurological …

Neuropsychiatric research has utilized cognitive testing in rodents to improve our
understanding of cognitive deficits and for preclinical drug development. However, more …

The 5‐choice serial reaction time task (5‐CSRTT) is the most widely used test to measure
attentional performance in rodents. The basic test design involves training animals to …

Background The 5 choice serial reaction time task (5CSRTT) is commonly used to assess
attention in rodents. We sought to develop a variant of the 5CSRTT that would speed …

Rats were trained to respond to the lever above which a light stimulus was briefly (0.5 s)
presented at unpredictable times. Once the task had been learned to criterion, subjects were …

BACKGROUND: Attentional deficits accompany many psychiatric disorders, underscoring
the need for rodent models of attention to screen novel therapeutic agents and characterize …